切换至 "中华医学电子期刊资源库"

中华普外科手术学杂志(电子版) ›› 2021, Vol. 15 ›› Issue (04) : 400 -403. doi: 10.3877/cma.j.issn.1674-3946.2021.04.013

论著

基于CT三层四分法的经腹入路腹腔镜手术治疗胃食管交界肿瘤的临床价值
王嘉玮1,(), 游庆军1, 李晓林1, 贾一飞1, 段超1   
  1. 1. 214000 江苏无锡,江南大学附属医院(无锡市第四人民医院)
  • 收稿日期:2020-06-13 出版日期:2021-08-17
  • 通信作者: 王嘉玮

Clinical value of laparoscopic surgery based on CT three-layer quartet for the treatment of gastroesophageal junction tumor

Jiawei Wang1,(), Qingjun You1, Xiaolin Li1, Yifei Jia1, Chao Duan1   

  1. 1. Affiliated Hospital of Jiangnan University (Wuxi Fourth People’s Hospital) Wuxi, Jiangsu 214000, China
  • Received:2020-06-13 Published:2021-08-17
  • Corresponding author: Jiawei Wang
  • Supported by:
    Project: national natural science foundation of China(70963001)
引用本文:

王嘉玮, 游庆军, 李晓林, 贾一飞, 段超. 基于CT三层四分法的经腹入路腹腔镜手术治疗胃食管交界肿瘤的临床价值[J]. 中华普外科手术学杂志(电子版), 2021, 15(04): 400-403.

Jiawei Wang, Qingjun You, Xiaolin Li, Yifei Jia, Chao Duan. Clinical value of laparoscopic surgery based on CT three-layer quartet for the treatment of gastroesophageal junction tumor[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(04): 400-403.

目的

探讨基于CT三层四分法的经腹入路腹腔镜手术治疗II型胃食管交界肿瘤的临床价值。

方法

回顾性分析2015年2月至2019年3月行腹腔镜手术治疗的100例CT三层四分法分型为II型胃食管交界肿瘤患者资料;根据手术入路方式不同将其分为两组,46例经胸腹入路(胸腹组),54例经腹入路(经腹组)。术后随访截止至2020年3月,统计生存情况。选用SPSS 22.00统计软件进行数据分析,围术期各项指标等计量资料用(±s)表示,采用独立t检验;切缘阳性率、并发症发生情况等计数资料采用χ2检验。绘制生存曲线图采用Kaplan-Meier检验,P<0.05为差异有统计学意义。

结果

两组患者均顺利完成手术,经腹组手术时间、清扫淋巴结数目、术后住院时间均明显优于胸腹组(P<0.05);经腹组术后并发症发生率为7.4%(4/54)远小于胸腹组的23.9%(11/46),差异有统计学意义(P<0.05);100例患者均获得确切随访,经腹组总生存率为81.5%,胸腹组为80.4%,两组比较差异无统计学意义(P=0.861)。

结论

基于CT三层四分法分型为II型胃食管交界肿瘤相比于经胸腹联合入路,经腹入路腹腔镜手术安全性高,可显著缩短手术时间、住院时间,清扫更多的淋巴结,具有较高的临床价值。

Objective

To explore the clinical value of laparoscopic operation through the abdominal three-layer quadrant CT in the treatment of type II gastroesophageal junction tumors.

Methods

Retrospective analysis was conducted on the data of 100 patients with type II gastroesophageal junction tumor who underwent laparoscopic surgery from February 2015 to March 2019 and were classified by three-slice CT quartet. According to different surgical approaches, the patients were divided into two groups: 46 patients (thoracoabdominal group) and 54 patients (abdominal group). Postoperative follow-up was conducted until March 2020, and survival was counted. SPSS 22.00 statistical software was used for data analysis, measurement data of various indicators during perioperative period were expressed as (±s), the independent t test was used; The positive rate of surgical margin and the incidence of complications were counted by χ2 test. Kaplan-Meier test was used to draw survival curves, and P<0.05 was considered statistically significant.

Results

The operation was completed successfully in both groups. The operative time, number of dissected lymph nodes and postoperative hospitalization time in the transabdominal group were significantly better than those in the thoracoabdominal group (P<0.05). The incidence of postoperative complications in the transabdominal group was 7.4% (4/54), which was much lower than that in the thoraco-abdominal group (23.9%, 11/46), and the difference was statistically significant (P<0.05). All the 100 patients were followed up accurately. The overall survival rate was 81.5% in the abdominal group and 80.4% in the thoracic and abdominal group, and there was no significant difference between the two groups (P=0.861).

Conclusion

Compared with the transthoracic-abdominal approach, transabdominal laparoscopic surgery is safer, which can significantly shorten the operation time and hospitalization time, and remove more Lymph nodes has high clinical value.

表1 100例AEG患者不同手术入路方式两组患者一般资料比较[(±s),例]
表2 100例AEG患者不同手术入路方式两组患者围手术期指标比较( ±s)
表3 100例AEG患者不同手术入路方式两组患者术后并发症指标比较(例)
图1 100例AEG患者不同手术入路方式两组患者累计生存率比较
[1]
谭锋维,薛奇,牟巨伟,等.从最新指南解读食管胃交界部腺癌的外科治疗[J].临床外科杂志,2018,26(9):641-643.
[2]
Kim HJ, Chung H, Shin SK, et al.Comparison of long-term clinical outcomes between endoscopic and surgical resection for earlystage adenocarcinoma of the esophagogastric junction[J].Surg Endosc, 2018, 32(8): 3540-3547.
[3]
赵玉洲,韩广森,马鹏飞,等.食管胃交界部腺癌CT分型与手术入路选择[J].中华医学杂志,2017,97(9):687-690.
[4]
Kurokawa Y, Yamaguchi T, Sasako M, et al.Institutional variation in short- and long-term outcomes after surgery for gastric or esophagogastric junction adenocarcinoma: correlative study of two randomized phase III trials ( JCOG9501 and JCOG9502) [J].Gastric Cancer, 2017, 20(3): 508-516.
[5]
赵巍,王小平,周勇安,等.手术入路对I、Ⅱ型食管胃结合部腺癌PN分期的影响[J].现代肿瘤医学,2016,24(18) :2895-2898.
[6]
Siewert JR, Stein HJ. Classification of adenocarcinoma of the oesophagogastric junction[J].Br J Surg, 1998, 85(11): 1457-1459.
[7]
杨勇,李卫平,熊辉,等.食管胃结合部腺癌的研究进展[J].中国普外基础与临床杂志,2017,24(6):765-769.
[8]
曹晖,赵恩吴.食管胃结合部腺癌的外科治疗策略[J].中华消化外科杂志,2016,15(11): 1048-1051.
[9]
刘晶晶,刘天舟,马志明,等.完全腹腔镜下经胸腔治疗SiewertⅡ型食管胃结合部腺癌[J].中华胃肠外科杂志,2019,22(2):126-127.
[10]
周瑜,施贵冬,田东,等.三种不同手术方式治疗进展期SiewertⅡ型食管胃结合部腺癌术后生活质量测评的比较[J].中国胸心血管外科临床杂志,2019,26(11):1079-1087.
[11]
邹贵军,王迪,胡时栋,等.腹腔镜与开腹胃癌根治术幽门下淋巴结清扫的临床疗效分析[J].解放军医学院学报,2017,38(5):402-405.
[12]
Duan X, Shang X, Tang P, et al. Lymph node dissection for Siewert II esophagogastric junction adenocarcinoma: a retrospective study of 136 cases[J]. ANZ J Surg, 2018, 88(4): E264-E267.
[13]
李哲. 两种手术入路对Ⅱ、Ⅲ型食管胃结合部腺癌患者术后存活期的影响[J].中国实用医刊,2016,43(4):64-66.
[14]
Zhu K, Xu Y, Fu J, et al. Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry[J]. Dis Marker, 2019, 2019: 9637972.
[15]
张国超,赵格非,薛奇.以手术为主的食管胃交界部腺癌综合治疗研究进展[J].肿瘤研究与临床,2017,29(11):788-792.
[1] 韩丹, 王婷, 肖欢, 朱丽容, 陈镜宇, 唐毅. 超声造影与增强CT对儿童肝脏良恶性病变诊断价值的对比分析[J]. 中华医学超声杂志(电子版), 2023, 20(09): 939-944.
[2] 郏亚平, 曾书娥. 含鳞状细胞癌成分的乳腺化生性癌的超声与病理特征分析[J]. 中华医学超声杂志(电子版), 2023, 20(08): 844-848.
[3] 钱龙, 陆晓峰, 王行舟, 杜峻峰, 沈晓菲, 管文贤. 神经系统调控胃肠道肿瘤免疫应答研究进展[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 86-89.
[4] 曹长青, 郭新艳, 高源, 张存, 唐海利, 樊东, 杨小军, 张松, 赵华栋. 肿瘤微环境参与介导HER2阳性乳腺癌曲妥珠单抗耐药的研究进展[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 90-95.
[5] 燕速, 霍博文, 徐惠宁. 4K荧光腹腔镜扩大右半结肠CME+D3根治术及No.206、No.204组淋巴结清扫术[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 14-14.
[6] 姚宏伟, 魏鹏宇, 高加勒, 张忠涛. 不断提高腹腔镜右半结肠癌D3根治术的规范化[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 1-4.
[7] 杜晓辉, 崔建新. 腹腔镜右半结肠癌D3根治术淋巴结清扫范围与策略[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 5-8.
[8] 周岩冰, 刘晓东. 腹腔镜右半结肠癌D3根治术消化道吻合重建方式的选择[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 9-13.
[9] 唐旭, 韩冰, 刘威, 陈茹星. 结直肠癌根治术后隐匿性肝转移危险因素分析及预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 16-20.
[10] 张生军, 赵阿静, 李守博, 郝祥宏, 刘敏丽. 高糖通过HGF/c-met通路促进结直肠癌侵袭和迁移的实验研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 21-24.
[11] 张焱辉, 张蛟, 朱志贤. 留置肛管在中低位直肠癌新辅助放化疗后腹腔镜TME术中的临床研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 25-28.
[12] 李凤仪, 李若凡, 高旭, 张超凡. 目标导向液体干预对老年胃肠道肿瘤患者术后血流动力学、胃肠功能恢复的影响[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 29-32.
[13] 李建美, 邓静娟, 杨倩. 两种术式联合治疗肝癌合并肝硬化门静脉高压的安全性及随访评价[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 41-44.
[14] 王军, 刘鲲鹏, 姚兰, 张华, 魏越, 索利斌, 陈骏, 苗成利, 罗成华. 腹膜后肿瘤切除术中大量输血患者的麻醉管理特点与分析[J]. 中华临床医师杂志(电子版), 2023, 17(08): 844-849.
[15] 徐军, 姬园园, 陈君平, 王健. 伴菊形团结构的脑膜瘤合并颅骨侵犯一例并文献复习[J]. 中华临床医师杂志(电子版), 2023, 17(08): 916-919.
阅读次数
全文


摘要