探讨腹腔镜下全系膜切除的结肠癌根治术对患者近远期预后的影响。

回顾性收集2008年4月至2013年4月间收治的80例结肠癌患者的临床资料，按照手术方式不同分为腔镜组和开腹组，各40例，分别接受腹腔镜下全结肠系膜切除术和传统开腹术。采用统计学软件SPSS21.0进行分析，两组患者近期疗效指标的比较采用独立样本t检验；术后并发症发生率及远期预后指标的比较采用χ²检验。P<0.05差异有统计学意义。

腔镜组患者的术中出血量、肛门排气时间均少于开腹组(均P<0.05)，淋巴结清扫数目多于开腹组(P<0.05)；两组患者手术时间及住院时间差异均无统计学意义(均P>0.05)；腔镜组术后并发症总发生率为5.0%，低于开腹组的22.5%，而差异无统计学意义(χ²＝3.5294, P>0.05)；腔镜组患者5年复发率为10.0%，显著低于开腹组的30.0%(χ²＝5.000, P<0.05)；腔镜组5年生存率为95.0%，显著高于开腹组的80.0%(χ²＝6.274, P<0.05)。

腹腔镜下全系膜切除术治疗结肠癌，可降低患者术中出血量，缩短肛门排气时间，淋巴结清扫较为彻底，近远期疗效均优于传统开腹术，值得推广应用。

To investigate the effect of laparoscopic complete mesocolic excision of colon cancer on short-term and long-term prognosis of patients.

The clinical data of 80 patients with colon cancer admitted to our hospital from April 2008 to April 2013 were retrospectively collected. The patients were divided into laparoscopic group and open group according to different surgical methods, each 40 cases. They were given laparoscopic complete mesocolic radical resection and traditional laparotomy respectively. Data analysis was performed by statistical software SPSS21.0. The short-term efficacy index of the two groups was compared by two independent samples t test. The complication rate and long-term prognosis of the two groups were compared by χ² test.

The intraoperative blood loss and anal exhaust time of the laparoscopic group were shorter than those of the open group (P<0.05), and the number of lymph node dissection was more than that of the open group (P<0.05). There was no significant difference in operation time and hospitalization time between the two groups (all P>0.05); The total incidence of postoperative complications in the laparoscopic group was 5.0%, which was lower than 22.5% in the open group, but the difference was not statistically significant (χ² =3.5294, P>0.05). The 3-year recurrence rate was 10.0% in the laparoscopic group, which was significantly lower than 30.0% in the open group. The difference was statistically significant χ² =5.0000, P<0.05). The 3-year survival rate in the laparoscopic group was 95.0%, which was significantly higher than 80.0% in the open group. The difference was statistically significant (χ² =6.2745, P<0.05).

Laparoscopic complete mesocolic excision for the treatment of colon cancer can significantly reduce intraoperative blood loss, shorten anal exhaust time, which lymph node dissection was complete, complication rate is lower, and short-term and long-term prognosis are all better, the effect is significant and it is worthy of promotion and application.