切换至 "中华医学电子期刊资源库"

中华普外科手术学杂志(电子版) ›› 2026, Vol. 20 ›› Issue (02) : 179 -182. doi: 10.3877/cma.j.issn.1674-3946.2026.02.021

论著

荧光腹腔镜下经胆囊管行胆总管取石术治疗胆总管结石的临床探讨
陈志1,2,(), 童智慧2,3, 张敬柱2,3, 汪鹏2,3   
  1. 1226500 江苏南通,南京中医药大学如皋附属医院(如皋市中医院)普外科
    2210000 南京,南京中医药大学
    3210000 南京,南京中医药大学金陵临床医学院普外科研究所
  • 收稿日期:2025-07-04 出版日期:2026-04-26
  • 通信作者: 陈志

Clinical discussion on the treatment of common bile duct stones by trans-cystic duct cholangioplasty under fluorescence laparoscopy

Zhi Chen1,2,(), Zhihui Tong2,3, Jingzhu Zhang2,3, Peng Wang2,3   

  1. 1Department of General Surgery, Rugao Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nantong Jiangsu Province 226500, China
    2Nanjing University of Traditional Chinese Medicine, Nanjing Jiangsu Province 210000, China
    3Institute of General Surgery, Jinling Clinical Medical College, Nanjing University of Traditional Chinese Medicine, Nanjing Jiangsu Province 210000, China
  • Received:2025-07-04 Published:2026-04-26
  • Corresponding author: Zhi Chen
  • Supported by:
    Nantong Basic Science Research and Social and People’s Livelihood Science and Technology Program(TKZ [2022] No.93)
引用本文:

陈志, 童智慧, 张敬柱, 汪鹏. 荧光腹腔镜下经胆囊管行胆总管取石术治疗胆总管结石的临床探讨[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 179-182.

Zhi Chen, Zhihui Tong, Jingzhu Zhang, Peng Wang. Clinical discussion on the treatment of common bile duct stones by trans-cystic duct cholangioplasty under fluorescence laparoscopy[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2026, 20(02): 179-182.

目的

探讨在腹腔镜下采用经胆囊管手术路径行胆总管探查取石的可行性、安全性。

方法

回顾性分析2020年11月至2024年10月54例胆总管结石合并胆囊结石患者临床资料,其中男性30例,女性24例,年龄(66.9±9.7)岁。根据手术方式不同分为两组,行吲哚菁绿(ICG)荧光腹腔镜经胆囊管行胆管探查取石(LTCBDE)术24例为观察组,行ICG荧光腹腔镜胆总管切开取石术(LCBDE)30例为对照组。比较两组患者胆囊管、肝总管、胆总管三管识别时间、胆管探查及取石时间、手术时间、术中出血量;手术成功率、结石清除率、术后住院时间、住院费用、并发症情况等指标。采用SPSS 26.0统计学软件分析数据。正态分布的计量资料以(±s)表示,两组间比较行独立样本t检验。计数资料以[例(%)]表示,两组间比较采用χ2检验或Fisher确切概率法。P<0.05为差异有统计学意义。

结果

两组患者手术均成功实施,三管识别时间、术中出血量、手术成功率比较差异无统计学意义(均P>0.05);而观察组患者胆管探查及取石时间、手术时间均较对照组短,差异有统计学意义(均P<0.05)。两组患者手术并发症发生率、住院总治疗费用比较差异无统计学意义(P>0.05),但患者术后住院时间及负压引流管带管的时间差异有统计学意义(均P<0.05)。

结论

对于部分胆囊结石合并胆总管结石或者具备胆总管探查指征的患者,经胆囊管行胆总管探查、取石是一种安全可行的外科手术方式,从而避免行胆总管切开,且可以避免术后带T管影响患者的生活质量,减少术后住院时间及负压引流管带管时间,值得在临床推广开展。

Objective

To explore the feasibility and safety of performing common bile duct exploration and stone removal through the cystic duct surgical approach under laparoscopy.

Methods

The clinical data of 54 patients with common bile duct stones and gallbladder stones from November 2020 to October 2024 were retrospectively analyzed. Among them, 30 were male and 24 were female, with an average age of (66.9±9.7) years. The patients were divided into two groups based on different surgical methods: 24 cases underwent indocyanine green (ICG) fluorescence laparoscopic cystic duct common bile duct exploration and stone removal (LTCBDE), and 30 cases underwent ICG fluorescence laparoscopic common bile duct incision and stone removal (LCBDE). The comparison included the time for identifying the cystic duct, common bile duct, and common duct, the time for common bile duct exploration and stone removal, the operation time, intraoperative blood loss; the success rate of the operation, stone clearance rate, postoperative hospital stay, hospitalization cost, and complications. Data were analyzed using SPSS 26.0 statistical software. Quantitative data with normal distribution were expressed as (±s), and comparisons between the two groups were performed using independent sample t tests. Count data were expressed as [cases (%)], and comparisons were conducted using the χ2 test or Fisher’s exact probability method. P<0.05 was considered statistically significant.

Results

Both groups successfully underwent the surgery. There were no statistically significant differences in the time for identifying the cystic duct, intraoperative blood loss, and operation success rate between the two groups (all P>0.05); however, the observation group had shorter time for common bile duct exploration and stone removal, and shorter operation time compared with the control group (all P<0.05). There was no statistically significant difference in the incidence of surgical complications and total hospitalization cost between the two groups (P>0.05), but there were statistically significant differences in the postoperative hospital stay and the duration of negative pressure drainage tube placement (all P<0.05).

Conclusion

For patients with gallbladder stones and common bile duct stones or those with indications for common bile duct exploration, performing common bile duct exploration and stone removal through the cystic duct is a safe and feasible surgical method, which avoids common bile duct incision and can avoid the impact of T-tube placement on the patient’s quality of life after surgery, reduces the postoperative hospital stay and the duration of negative pressure drainage tube placement, and is worthy of clinical promotion and implementation.

表1 腹腔镜下胆总管取石术两组患者一般资料比较
图1 胆总管结石及经胆囊管行输尿管软镜探查胆管
图2 LC+LTCBDE相关手术操作步骤腹腔镜视频图像注:A为ICG荧光模式下肝外胆管的显影,明确三管结构:胆囊管、肝总管、胆总管;B为普通显示界面下的三管结构;C为尖刀片切开胆囊管;D为输尿管软镜经胆囊管探查胆总管;E为输尿管软镜经胆囊管探查胆总管及肝内胆管;F显示的是经胆囊管取出的多枚胆总管结石
表2 腹腔镜下胆总管取石术两组患者手术相关指标比较
表3 腹腔镜下胆总管取石术两组患者术后相关指标比较
[1]
田宏亮, 柏斗胜, 金圣杰, 等. 同期腹腔镜胆囊切除联合腹腔镜胆总管探查术或内镜括约肌切开取石术治疗胆囊结石合并胆总管结石的疗效比较[J]. 中华普通外科杂志, 2024, 39(02): 105-109.
[2]
张军, 李立强, 姜友, 等. 腹腔镜胆囊切除联合胆总管切开取石在胆囊结石合并正常直径胆总管结石患者中的应用[J]. 中华普通外科杂志, 2023, 38(03): 189-192.
[3]
O’Neill AM, Anderson K, Baker LK, et al. The overall poor specificity of MRCP in the preoperative evaluation of the jaundiced patient will increase the incidence of nontherapeutic ERCP [J]. Am Surg, 2020, 86(8): 1022-1025.
[4]
金明明, 董明豪, 李永利. ERCP联合LC同期治疗胆囊结石合并胆总管结石的效果分析[J]. 中国实用医刊, 2024, 51(20): 20-23.
[5]
金震东. ERCP在胆管结石诊治中的守正与创新[J]. 中华肝胆外科杂志, 2025, 31(06): 401-405.
[6]
段建文, 袁磊, 孙运鹏, 等. 腹腔镜一步法与内镜联合腹腔镜两步法治疗80岁以上胆囊结石合并胆总管结石的疗效比较[J]. 中华肝胆外科杂志, 2023, 29(03): 185-189.
[7]
李进昂, 瞿康林, 庞青, 等. 双镜探查后一期缝合治疗老年胆囊结石合并胆总管结石的临床疗效分析[J/OL]中华普通外科学文献(电子版), 2022, 16(03): 183-187.
[8]
赵畅, 杨毅, 唐华勇, 等. 三镜联合与双镜联合治疗胆囊结石合并胆总管结石的临床疗效比较[J/OL]中华肝脏外科手术学电子杂志, 2025, 14(03): 408-415.
[9]
成时保, 胡伟, 温崇煜, 等. 腹腔镜下运用输尿管软镜行经胆囊管胆总管探查取石术的临床疗效分析[J]. 中华肝胆外科杂志, 2025, 31(02): 92-95.
[10]
武亚东, 汪栋, 徐维宇, 等. 日间手术与次日出院的腹腔镜经胆囊管胆道探查取石术回顾性病例对照研究[J]. 国际外科学杂志, 2022, 49(12): 825-832.
[11]
周标, 陈达伟, 汤晓东, 等. 腹腔镜下经胆囊管汇入部微切开取石在细径胆总管结石合并胆囊结石中的应用[J/OL]中华肝脏外科手术学电子杂志, 2023, 12(04): 422-426.
[12]
周佳, 杨璐, 孙正豪, 等. 胆道微生态与胆总管结石相关性研究进展[J]. 中华消化杂志, 2025, 45(05): 351-355.
[13
陈浩, 林梁, 马克强, 等. 胆道镜下放置胆道支架在胆总管结石并急性胆管炎中的应用[J/OL]中华普通外科学文献(电子版), 2023, 17(02): 110-114.
[14]
陈海川, 王哲近, 宋洪亮. 胆总管结石患者胆总管探查术前Oddi括约肌功能影响因素分析[J]. 中华肝胆外科杂志, 2025, 31(07): 529-533.
[1] 彭兵. 联合血管切除重建的腹腔镜胰十二指肠切除术实践与探索[J/OL]. 中华普通外科学文献(电子版), 2026, 20(1): 23-23.
[2] 杜峻峰, 吕远, 孙亮. 全腹腔镜下远端胃癌根治术(Billroth Ⅱ+Braun吻合)[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 115-115.
[3] 燕速, 赵康, 谢宏宇, 霍博文, 梁浩, 李园园, 刘云荣. 无助手减孔腹腔镜SiewertⅡ型食管胃结合部癌根治术[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 116-116.
[4] 戴红梅, 李双喜, 李子禹. 我国腹腔镜胃癌手术治疗现状与未来[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 103-107.
[5] 王萌, 管文贤. 我国腹腔镜胃癌根治关键技术与质量控制[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 108-110.
[6] 李玮璇, 杜峻峰, 李世拥. 我国腹腔镜胃癌根治术主要并发症与处理[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 111-114.
[7] 王瑞, 张建, 乔美美, 闫星宇, 赵世男. 完全腹腔镜经腹经膈肌裂孔入路SiewertⅡ型食管胃结合部腺癌根治术临床效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 121-124.
[8] 朱田雨, 施海, 杨洁. 预先小切口辅助腹腔镜根治术治疗进展期远端胃癌的临床研究[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 130-133.
[9] 汝干, 翟春涛, 田昳程, 陈正荣. 腹腔镜下不同手术方式治疗cT1N0M0期胃癌的临床比较[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 134-137.
[10] 李广鑫, 权慧娟, 高志娟, 李良, 王肖君, 曹玉庆. 腹腔镜急诊切除与支架置入限期切除治疗梗阻性结直肠癌的临床效果比较[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 142-145.
[11] 范现英, 路萌, 刘晓晴, 张希为, 胡延伟, 连彦军. 腹腔镜结直肠癌切除经不同自然腔道标本取出术治疗女性患者的临床比较[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 146-149.
[12] 周放, 刘海晨, 王宇超, 郭健, 石志良, 周国强, 沈成龙. "三孔法"腹腔镜手术治疗急性乙状结肠穿孔的临床应用[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 154-157.
[13] 陈玉, 韩戟, 杨力. CT血管成像对肠系膜下动脉分型评估及腹腔镜直肠癌手术的指导价值[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 162-165.
[14] 蒋春雷, 崔静, 周晨, 王少军, 魏晓为. 头尾侧联合入路腹腔镜根治术治疗右半结肠癌效果[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 166-169.
[15] 贺智恒, 姚德炯, 孙东方. 腹腔镜下胆囊切除术后胆瘘影响因素分析及风险预测模型的构建[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(02): 175-178.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?