切换至 "中华医学电子期刊资源库"

中华普外科手术学杂志(电子版) ›› 2021, Vol. 15 ›› Issue (05) : 539 -541. doi: 10.3877/cma.j.issn.1674-3946.2021.05.020

论著

保留盆腔自主神经的腹腔镜全直肠系膜切除术在男性直肠癌患者中的应用
赵强1, 冯树森1, 张东成1, 郭奇1, 谭望1, 周述芝2,()   
  1. 1. 625000 四川雅安,雅安市人民医院胃肠甲乳外科
    2. 625000 四川雅安,雅安市人民医院麻醉科
  • 收稿日期:2020-12-09 出版日期:2021-10-26
  • 通信作者: 周述芝

Laparoscopic total mesorectal excision with pelvic autonomic nerve preservation in male patients with rectal cancer

Qiang Zhao1, Shusen Feng1, Dongcheng Zhang1, Qi Guo1, Wang Tan1, Shuzhi Zhou2,()   

  1. 1. Department of Gastrointestinal and Breast Surgery, Ya’an People’s Hospital, Sichuan 625000, China
    2. Department of Anesthesiology, Ya’an People’s Hospital, Sichuan 625000, China
  • Received:2020-12-09 Published:2021-10-26
  • Corresponding author: Shuzhi Zhou
  • Supported by:
    Scientific Research Project of Sichuan Medical Association(S18029); Sichuan Provincial Health Appropriate Technology Extension Project(19SYJS21)
引用本文:

赵强, 冯树森, 张东成, 郭奇, 谭望, 周述芝. 保留盆腔自主神经的腹腔镜全直肠系膜切除术在男性直肠癌患者中的应用[J]. 中华普外科手术学杂志(电子版), 2021, 15(05): 539-541.

Qiang Zhao, Shusen Feng, Dongcheng Zhang, Qi Guo, Wang Tan, Shuzhi Zhou. Laparoscopic total mesorectal excision with pelvic autonomic nerve preservation in male patients with rectal cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(05): 539-541.

目的

探讨腹腔镜全直肠系膜切除术(TME)中保留盆腔自主神经(PANP)对男性直肠癌患者排尿功能、性功能的影响及其应用效果。

方法

回顾性选取2016年8月至2019年10月153例行TME+PANP的男性直肠癌患者,根据手术方式分为开腹组82例和腹腔镜组71例。观察两组患者术后排尿功能、性功能障碍率及术后1年局部复发情况,评价其疗效。采用统计软件SPSS 21.0进行数据分析处理,排尿功能计量资料用(±s)表示,采用独立样本t检验;性功能及复发率等计数资料采用χ2检验,排尿功能采用秩和检验;P<0.05表示差异有统计学意义。

结果

术后3个月,腹腔镜组膀胱最大容量、最大尿流量、残尿量及排尿功能障碍率优于开腹组(P<0.05);勃起功能障碍率和射精功能障碍率低于开腹组(P<0.05)。术后1年两组局部复发率(2.8% vs. 6.1%)组间差异无统计学意义(χ2=0.938,P=0.333)。

结论

腹腔镜全直肠系膜切除术中保留盆腔自主神经能够有效改善男性患者术后排尿功能、性功能障碍,可在临床推广应用。

Objective

To investigate the effect of pelvic autonomic nerve preservation (PANP) in laparoscopic total mesorectal resection (TME) in terms of urinary function and sexual function of male patients with rectal cancer.

Methods

Clinical data of 153 male patients with rectal cancer treated with TME+ PANP from August 2016 to October 2019 were analyzed retrospectively. According to the surgical methods, 82 patients were divided into the open group and 71 cases into the laparoscopic group. The postoperative urination function, sexual function, dysfunction rate and local recurrence in both groups were observed, and the efficacy was evaluated. Statistical analysis were performed by using SPSS 21.0 software. The measurement data of urination function were expressed as(±s), and were examined by using independent t test. Count data such as sexual function and recurrence rate were analyzed by using χ2 test, and the urination function was analyzed by using rank sum test. A P value of <0.05 was considered as statistically significant difference.

Results

Three months after the operation, the maximum bladder volume, maximum urine flow, residual urine volume and the rate of urinary dysfunction in the laparoscopic group were much better than those in the open group respectively (P<0.05); The rates of erectile dysfunction and ejaculation dysfunction were much lower than those of the open group respectively (P<0.05). One year after surgery, there was no significant difference between the two groups in local recurrence rate of (2.8% vs. 6.1%, P>0.05).

Conclusion

Pelvic autonomic nerve preservation during laparoscopic total mesorectal resection could effectively improve postoperative urination function and sexual dysfunction of male patients, which would be popular in clinical application.

表1 153例男性直肠癌患者不同术式两组患者一般资料比较[(±s),例]
表2 153例男性直肠癌患者不同术式两组术后排尿功能相关指标比较[(±s),例]
表3 153例男性直肠癌患者不同术式两组术后性功能比较[例(%)]
[1]
Beaulieu J-F. Colorectal Cancer Research: Basic,Preclinical,and Clinical Approaches[J]. Cancers, 202012(2):416.
[2]
刘思达,刘栋,段降龙. 腹腔镜辅助经肛门全直肠系膜切除术与全直肠系膜切除术的临床对比研究[J/CD]. 中华普外科手术学杂志(电子版)202014(1):42-45.
[3]
申占龙,叶颖江,王杉. 直肠癌全直肠系膜切除术中盆腔植物神经的易损区域及保护[J/CD]. 中华结直肠疾病电子杂志20187(1):8-11.
[4]
邓伟,劳景茂,韦小波. 腹腔镜直肠癌根治术保留Denonvilliers筋膜对男性患者术后排尿及性功能的影响分析[J]. 结直肠肛门外科201925(2):156-159.
[5]
冯波,苏浩. 腹腔镜直肠癌根治术中保留盆自主神经的关键技术与意义[J/CD]. 中华普外科手术学杂志(电子版)201913(1):8-12.
[6]
赵启生,杨贵义,刘彦. 腹腔镜及开腹直肠癌根治术中保留自主神经的效果比较[J/CD].中华普外科手术学杂志(电子版)201812(1):30-34.
[7]
Saito N, Sarashina H, Nunomura M, et al. Clinical evaluation of nervesparing surgery combined with preoperative radiotherapy in advanced rectal cancer patients[J]. Am J Surg1998175(4):277-282.
[8]
王剑,熊辉,郑晓峰. 全直肠系膜切除术联合自主神经保留术对男性直肠癌患者性功能及排尿功能的影响[J]. 中国性科学2019, 28(8):5-7.
[9]
Deng WH, , Zheng YB, , Tong SL , et al. Efficiency analysis on functional protection of nerve plane-oriented laparoscopic total mesorectal excision[J]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2019, 22(12):1144-1151.
[10]
周声宁,韩方海. 腹腔镜下直肠癌根治术保留自主神经的解剖和技术要点[J/CD]. 中华结直肠疾病电子杂志20198(1):6-11.
[11]
张海永,杨鹏远,兰海生,等. 以盆腔自主神经为解剖标识的腹腔镜低位直肠癌根治术对男性患者术后排尿、性功能影响的研究[J]. 结直肠肛门外科201824(1):22-26.
[12]
韩方海,钟广宇. 直肠癌全直肠系膜切除手术中保护盆腔自主神经的技术路径[J]. 临床外科杂志202028(5):412-415.
[13]
金旦娟,李震洋,顾晓冬,等. 腹腔镜中低位直肠癌根治术中盆腔自主神经监测(IMPAN)的价值[J]. 复旦学报(医学版)202047(5):669-678.
[14]
杨丹,李丽,邵丽. 腹腔镜下系统保留盆腔自主神经的直肠癌根治术的近期疗效及对患者术后排尿、胃肠功能影响[J]. 实用癌症杂志202035(5):819-824.
[15]
丁鹏,谢方利,刘海科,等. 保留自主神经的腹腔镜直肠癌切除术效果研究及腹膜后自主神经的筋膜解剖学观察[J/CD]. 中华普外科手术学杂志(电子版)202115(1):35-38.
[16]
燕速,Chon Seung-Hun,马新福,等. 腹腔镜直肠癌根治术筋膜解剖与自主神经保护再认识[J]. 中华消化外科杂志202019(10):1054-1061.
[1] 曹迪, 张玉茹. 经腹腔镜生物补片修补直肠癌根治术后盆底疝1例[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 115-116.
[2] 李凯, 陈淋, 向涵, 苏怀东, 张伟. 一种U型记忆合金线在经脐单孔腹腔镜阑尾切除术中的临床应用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 15-15.
[3] 杜晓辉, 崔建新. 腹腔镜右半结肠癌D3根治术淋巴结清扫范围与策略[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 5-8.
[4] 周岩冰, 刘晓东. 腹腔镜右半结肠癌D3根治术消化道吻合重建方式的选择[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 9-13.
[5] 唐旭, 韩冰, 刘威, 陈茹星. 结直肠癌根治术后隐匿性肝转移危险因素分析及预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 16-20.
[6] 张生军, 赵阿静, 李守博, 郝祥宏, 刘敏丽. 高糖通过HGF/c-met通路促进结直肠癌侵袭和迁移的实验研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 21-24.
[7] 张焱辉, 张蛟, 朱志贤. 留置肛管在中低位直肠癌新辅助放化疗后腹腔镜TME术中的临床研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 25-28.
[8] 王春荣, 陈姜, 喻晨. 循Glisson蒂鞘外解剖、Laennec膜入路腹腔镜解剖性左半肝切除术临床应用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 37-40.
[9] 李晓玉, 江庆, 汤海琴, 罗静枝. 围手术期综合管理对胆总管结石并急性胆管炎患者ERCP +LC术后心肌损伤的影响研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 57-60.
[10] 甄子铂, 刘金虎. 基于列线图模型探究静脉全身麻醉腹腔镜胆囊切除术患者术后肠道功能紊乱的影响因素[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 61-65.
[11] 逄世江, 黄艳艳, 朱冠烈. 改良π形吻合在腹腔镜全胃切除消化道重建中的安全性和有效性研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 66-69.
[12] 李三祥, 李佳, 刘俊峰, 吕东晨, 方晖东, 谭朝晖, 刘杰, 潘佐, 乔建坤. 基于CT影像的三维重建成像技术在腹腔镜大肾上腺肿瘤切除术中的应用[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 570-574.
[13] 赵佳晖, 王永兴, 彭涛, 李明川, 魏德超, 韩毅力, 侯铸, 姜永光, 罗勇. 后腹腔镜根治性肾切除手术时间延长和术中出血量增多的影响因素分析[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 575-580.
[14] 林文斌, 郑泽源, 郑文能, 郁毅刚. 外伤性脾破裂腹腔镜脾切除术患者中转开腹风险预测模型构建[J]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 619-623.
[15] 牛朝, 李波, 张万福, 靳文帝, 王春晓, 李晓刚. 腹腔镜袖状胃切除联合胆囊切除治疗肥胖合并胆囊结石安全性和疗效[J]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 635-639.
阅读次数
全文


摘要