在20世纪初期，腹腔镜手术在腹部外科领域取得了迅猛发展，其中腹腔镜结直肠癌根治术已经成为治疗的标准术式。结直肠癌在发展过程中有接近50%的患者会出现肝转移，随着靶向药物的以及多学科讨论策略的发展，越来越多的结直肠癌肝转移患者获得了根治性手术切除的机会。此外，3D腹腔镜、能量平台以及各种腔内闭合器械的出现，更是使腹腔镜肝转移癌切除手术得以实现，多个大规模的回顾性分析也证实了其安全性。然而，肝脏的解剖复杂、管道繁多且操作空间狭小，其手术难度较结直肠手术更高。本文就近20年腹腔镜肝转移癌手术的发展进行回顾与阐述。

In the early 20th century, laparoscopic surgery has been rapidly developed in abdominal surgery, among which laparoscopic radical resection has become the standard surgery for treatment. During the development of colorectal cancer, nearly 50% of patients will have liver metastasis. With the development of targeted drugs and multidisciplinary discussion strategies, more and more colorectal cancer patients with liver metastasis obtain the opportunity of radical resection. In addition, the emergence of 3D laparoscopy, energy platform and various endovascular closure devices make laparoscopic resection of liver metastases possible. A number of large-scale retrospective study have also confirmed its safety. However, due to the complexity of liver anatomy, various ducts and small space for operation, this kind of surgery is more difficult than colorectal surgery. In this paper, the development of laparoscopic surgery for liver metastases in recent 20 years was reviewed.