胃癌根治联合受累脏器切除可缓解一些局部晚期胃癌症状、改善生活质量、延长生存时间，甚至可以达到治愈。腹腔镜手术创伤小、出血少，术后恢复快，有经验的中心逐渐尝试胃癌根治联合被侵脏器切除术。常见的联合脏器切除包括联合脾脏切除、胆囊切除、胰体尾切除、胰十二指肠切除、肝切除和子宫双附件切除等。由于技术难度较大、学习曲线较长，开展的中心和病例数较少，其安全性、可行性和远期效果缺乏高级别的证据支持，需多中心的临床研究去验证。

Radical gastrectomy combined with combined organ resection could relieve symptoms, improve quality of life, prolong survival and even cure some locally advanced gastric cancer. Laparoscopic surgery has the advantages, such as minimal trauma, less bleeding and faster postoperative recovery. The experienced center has gradually attempted to apply to combined organ resection for gastric cancer, including combined with splenectomy, pancreatic body and tail, pancreaticoduodenectomy, cholecystectomy, liver resection, hysterectomy and bilateral oophorectomy. Due to technical difficulties, the long learning curve, less number of cases in current studies and the lack of control group, the safety, feasibility and long-term effect of laparoscopic combined combined organ resection for gastric cancer still require high level evidences, therefore more multicenter clinical trials should be performed deeply.