Abstract:
Objective To investigate the safety of Laparoscopy combined with duodenoscopy for the treatment of pancreatic pseudocysts complicated with severe acute pancreatitis and the improvement of inflammatory cytokines.
Methods A retrospective analysis of 86 patients with pancreatic pseudocysts complicated with severe acute pancreatitis from April 2015 to March 2017 was studied. According to the treatment plan, patients were divided into Laparoscopy combined with duodenoscopy group (n=46) and laparotomy group (n=40) In the Laparoscopy combined with duodenoscopy group, endoscopic and laparoscopic treatments were used. In the open group, traditional open surgery was used. SPSS20.0 statistical software was used to analyze. The incidence of complications between the two groups were compared using the χ2 test. The measurement data of each index and serum inflammatory factor level during the operation were expressed as (±s), and compared with Independent t test, P<0.05meant the difference was statistically significant.
Results The operation time, intraoperative blood loss, length of hospital stay and other surgical indicators in the Laparoscopy combined with duodenoscopy group were significantly lower than those in the open group (P<0.05); abdominal pain relief time, exhaust time, and body temperature recovery time in the Laparoscopy combined with duodenoscopygroup were significantly better than those in the open group (P<0.05); the incidence of postoperative complications in the Laparoscopy combined with duodenoscopy group was significantly lower than that in the open group (7.5% vs. 26.1%) (P<0.05); The levels of IL-18, IL-6 and TNF-α in the patients of the Laparoscopy combined with duodenoscopy group were significantly lower than those in the open group (P<0.05).
Conclusion The use of Laparoscopy combined with duodenoscopy to treat pancreatic pseudocysts complicated with severe acute pancreatitis has better surgical outcomes and fewer postoperative complications, which can effectively improve the patient’s clinical symptoms and is worthy of further clinical application.
Key words:
Pancreatitis, Acute Necrotizing,
Pancreatic Pseudocyst,
Laparoscopes,
Duodenoscopes,
Inflammation
Jianhui Ge, Yu Xu, Bin Wang, Youming Ding. Laparoscopy combined with duodenoscopy for the treatment of pancreatic pseudocysts complicated with severe acute pancreatitis and improvement of inflammatory cytokines[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(02): 200-202.