To compare the effect of laparoscopic-choledochoscopic gallbladder-preserving lithotripsy and laparoscopic cholecystectomy on complications and short-term living quality in gallstone patients.

116 gallstone patients in our hospital from January 2015 to January 2018 were selected, and they were divided into two groups by randomized double-blinded method. Laparoscopic cholecystectomy was performed in the laparoscopic group (n=58); and laparoscopic-choledochoscopic gallbladder-preserving lithotripsy was performed in the laparoscopic-choledochoscopic group (n=58). SPSS 21.0 software package was used to analyze the data of the whole group. The first-stage success rate of calculus removed and complications in the two groups were described with frequency and rate, and compared with χ² test; The surgical data, inflammatory factors and FACT-G score were recorded by (±s), and compared with independent t test, P<0.05 was considered statistically significant.

The intraoperative bleeding volume, anal exhaust time, postoperative 24 h numerical rating scale (NRS), hospital stays in laparoscopic-choledochoscopic group were lower than those in laparoscopic group (P<0.05); The IL-6 and CRP levels of the two groups at postoperative 3 d were increased, but the levels of laparoscopic-choledochoscopic group were lower than those of laparoscopic group (P<0.05); The first-stage success rate of calculus removed of laparoscopic-choledochoscopic group (94.8%) was higher than laparoscopic group (79.3%), and the incidence of complications (8.6%) was lower than laparoscopic group (22.4%) (P<0.05); After surgery for 3 months, the FACT-G scores of the two groups were increased compared with those before surgery, and the scores of laparoscopic-choledochoscopic group [(87.1±8.8) points] was higher than laparoscopic group [(67.3±9.5) points], and the difference was statistically significant (P<0.05).

Compared with laparoscopic cholecystectomy, laparoscopic-choledochoscopic gallbladder-preserving lithotripsy in treatment of gallstone has advantages such as less bleeding volume, high first-stage success rate of calculus removed and slight pain, it can decrease postoperative inflammatory response, reduce complications and increase short-term living quality.