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中华普外科手术学杂志(电子版) ›› 2025, Vol. 19 ›› Issue (05) : 527 -530. doi: 10.3877/cma.j.issn.1674-3946.2025.05.013

论著

适形保肛术对低位直肠癌患者术后肛门功能的影响研究
袁德玺1, 徐海霞2, 华秀丽3, 申青4,()   
  1. 1266000 山东青岛,青岛大学附属青岛市第三人民医院肛肠外科
    2266000 山东青岛,康复大学青岛中心医院核医学科
    3266000 山东青岛,康复大学青岛中心医院肿瘤科
    4266000 山东青岛,青岛心血管病医院健康管理中心普外科
  • 收稿日期:2025-03-28 出版日期:2025-10-26
  • 通信作者: 申青

A study on the effect of conformal anal-preserving surgery on postoperative anal function in patients with low rectal cancer

Dexi Yuan1, Haixia Xu2, Xiuli Hua3, Qing Shen4,()   

  1. 1Department of Anorectal Surgery, Qingdao Third People’s Hospital, Qingdao University, Qingdao Shandong Province 266000, China
    2Department of Nuclear Medicine
    3Department of Oncology, Qingdao Central Hospital, Rehabilitation University, Qingdao Shandong Province 266000, China
    4Department of General Surgery, Qingdao Cardiovascular Hospital Health Management Center Qingdao, Qingdao Shandong Province 266000, China
  • Received:2025-03-28 Published:2025-10-26
  • Corresponding author: Qing Shen
  • Supported by:
    Qingdao 2023 Annual Medical and Health Scientific Research Guidance Project(2023-WJDZ108)
引用本文:

袁德玺, 徐海霞, 华秀丽, 申青. 适形保肛术对低位直肠癌患者术后肛门功能的影响研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(05): 527-530.

Dexi Yuan, Haixia Xu, Xiuli Hua, Qing Shen. A study on the effect of conformal anal-preserving surgery on postoperative anal function in patients with low rectal cancer[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(05): 527-530.

目的

研究适形保肛术(CSPO)对低位直肠癌患者术后肛门功能的影响。

方法

回顾性收集2020年1月至2023年9月200例低位直肠癌患者临床资料,根据不同的腹腔镜术式,分为A组(n=67,行CSPO),B组(n=83,行经括约肌间切除术),C组(n=50,行改良Bacon术)。采用SPSS 24.0软件处理数据,围手术期指标等计量资料用(±s)表示,多组间比较采用F检验;吻合口漏发生率等计数资料用[例(%)]表示,组间比较采用χ2检验;等级资料行秩和检验;以Kaplan-Meier法绘制患者术后12个月无病生存曲线,行Log-Rank检验。检验水准α=0.05。

结果

所有患者无中转开腹手术病例,均行R0切除。三组患者淋巴结清扫数目、术后并发症Clavien-Dindo分级对比,差异无统计学意义(P>0.05);A组患者手术、排气、下床活动、住院时间均短于B组、C组(P<0.05);C组患者术中出血量少于A组、B组(P<0.05);B组患者吻合口狭窄发生率显著高于A、C组(P<0.05);C组患者吻合口漏发生率显著高于A、B组(P<0.05)。术前,三组患者生活质量评分比较,差异无统计学意义(P>0.05);术后12个月,三组患者功能领域评分均较术前提高,症状领域评分下降,但A、C组改善优于B组(P<0.05)。术后12个月,A组、B组、C组无病生存期对比,差异无统计学意义(P>0.05)。

结论

CSPO不仅能显著改善低位直肠癌患者术后肛门功能及长期生活质量,缩短手术时间,促进术后短期恢复,还能有效降低吻合口漏及吻合口狭窄的发生率。

Objective

To investigate the effect of conformal sphincter-preserving operation (CSPO) on postoperative anal function in patients with low rectal cancer.

Methods

Clinical data of 200 patients with low rectal cancer admitted to the hospital from January 2020 to September 2023 were retrospectively collected. According to different laparoscopic procedures, they were divided into group A (n=67, underwent conformal sphincter-preserving operation), group B (n=83, underwent intersphincteric resection), and group C (n=50, underwent modified Bacon procedure). SPSS 24.0 software was used for data processing. Measurement data such as perioperative indicators and quality of life scores were expressed as (±s), and multiple group comparisons were performed using F test. Enumeration data such as the incidence of anastomotic leakage and anastomotic stricture were expressed as [cases (%)], and intergroup comparisons were performed using chi-square test. Ranked data were expressed as the number of cases, and rank-sum test was used. Kaplan-Meier method was used to draw the disease-free survival curve at 12 months after surgery, and Log-Rank test was performed. The test level was α=0.05.

Results

All patients had no conversion to open surgery and underwent R0 resection. There were no statistically significant differences in the number of lymph nodes dissected and Clavien-Dindo grade of postoperative complications among the three groups (P>0.05). The operation time, exhaust time, ambulation time, and hospital stay in group A were shorter than those in groups B and C (P<0.05). The intraoperative blood loss in group C was less than that in groups A and B (P<0.05). The incidence of anastomotic stricture in group B was significantly higher than that in groups A and C (P<0.05). The incidence of anastomotic leakage in group C was significantly higher than that in groups A and B (P<0.05). Before surgery, there was no statistically significant difference in quality of life scores among the three groups (P>0.05). At 12 months after surgery, the functional domain scores of the three groups were higher than those before surgery, and the symptom domain scores decreased, but the improvement in groups A and C was better than that in group B (P<0.05). There was no statistically significant difference in disease-free survival (DFS) among groups A, B, and C at 12 months after surgery (P>0.05).

Conclusion

CSPO can not only significantly improve the postoperative anal function and long-term quality of life of patients with low rectal cancer, shorten the operation time, and promote short-term postoperative recovery, but also effectively reduce the incidence of anastomotic leakage and anastomotic stricture.

表1 三组低位直肠癌手术患者一般资料比较
表2 三组低位直肠癌手术患者围手术期指标对比(±s
表3 三组低位直肠癌手术患者生活质量评分对比(分,±s
图1 三组低位直肠癌手术患者术后12个月DFS曲线
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