近年来，胰头癌腹腔镜胰十二指肠切除术在我国发展迅速。但胰头癌易侵犯周围血管神经丛、易发生淋巴转移、常伴有慢性胰腺炎等特点，以及治疗理念的变迁、新辅助/转化治疗后手术病例的增加，使开展腹腔镜胰十二指肠切除术仍存在诸多难点。快速度过学习曲线、合理的根治性切除范围及简单高效安全的胰肠吻合是保障手术安全性并使患者最终获益的关键。规范化的培训和标准化的质量控制，将使腹腔镜胰十二指肠切除术进一步得到普及和发展，从而改善患者预后。

In recent years, laparoscopic pancreaticoduodenectomy (LPD) for pancreatic head cancer has developed rapidly in China. However, pancreatic head cancer is characterized by easy invasion of surrounding vascular nerve plexus, high propensity for lymphatic metastasis, and frequent association with chronic pancreatitis. Additionally, the evolution of treatment concepts and the increase in surgical cases following neoadjuvant/conversion therapy have posed numerous challenges to the implementation of LPD. Rapidly overcoming the learning curve, defining a reasonable radical resection margin, and performing simple, efficient, and safe pancreaticojejunostomy are crucial for ensuring surgical safety and ultimately benefiting patients. Standardized training and quality control will further promote the popularization and development of LPD, thereby improving patient outcomes.