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中华普外科手术学杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 87 -90. doi: 10.3877/cma.j.issn.1674-3946.2022.01.025

论著

全腹腔镜胰十二指肠切除术的预后研究
牛闻宇1,(), 支永发1, 张义1, 马明杰1, 周庆1   
  1. 1. 810000 青海西宁,青海红十字医院胃肠外科
  • 收稿日期:2021-01-25 出版日期:2022-02-26
  • 通信作者: 牛闻宇

Prognostic of total laparoscopic pancreaticoduodenectomy

Wenyv Niu1,(), Yongfa Zhi1, Yi Zhang1, Mingjie Ma1, Qing Zhou1   

  1. 1. Qinghai Red Cross Hospital gastrointestinal surgery, Xining Qinghai Province 81000, China
  • Received:2021-01-25 Published:2022-02-26
  • Corresponding author: Wenyv Niu
  • Supported by:
    Guiding project of health and family planning system in Qinghai Province in 2017(2017-wjzdx-78); Key projects of Qinghai health system in 2019(2019-wjzd-06)
引用本文:

牛闻宇, 支永发, 张义, 马明杰, 周庆. 全腹腔镜胰十二指肠切除术的预后研究[J/OL]. 中华普外科手术学杂志(电子版), 2022, 16(01): 87-90.

Wenyv Niu, Yongfa Zhi, Yi Zhang, Mingjie Ma, Qing Zhou. Prognostic of total laparoscopic pancreaticoduodenectomy[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(01): 87-90.

目的

探讨影响全腹腔镜胰十二指肠切除术(TLPD)患者预后的危险因素。

方法

回顾性选取2016年8月至2018年10月行TLPD术的57例壶腹周围癌患者临床资料。采用统计软件SPSS 20.0进行数据分析,计量资料采用(

xˉ
±s)表示,组间比较行t检验;计数资料采用例(%)表示,组间比较行χ2检验。采用K-M法绘制生存曲线分析患者术后生存情况;采用COX回归多因素分析影响TLPD术患者预后生存的独立危险因素。P<0.05为差异有统计学意义。

结果

57例患者术后均获得随访,中位随访时间为31个月,K-M生存曲线分析显示术后累积生存率为47.4%。单因素分析中有意义因素行COX回归多因素分析,结果显示临床T分期、淋巴结转移、脉管癌栓是影响TLPD患者预后生存的独立危险因素(P<0.05)。

结论

临床T分期、淋巴结转移、脉管癌栓是影响TLPD患者预后生存的独立危险因素,术前进行早期诊断及干预、治疗有望改善患者预后生存。

Objective

To investigate the risk factors affecting the prognosis of total laparoscopic pancreaticoduodenectomy(TLPD).

Methods

The clinical data of 57 patients with periampullary carcinoma who received TLPD from August 2016 to October 2018 were retrospectively selected. Statistical software SPSS 20.0 was used for data analysis. Statistical software SPSS 20.0 was used for data analysis. Measurement data were expressed by(

xˉ
±s),and t test was performed for comparison between groups. Enumeration data were expressed as n(%),and χ2 was used for comparison between groups. K-M method was used to draw the survival curve to analyze the postoperative survival of the patients. Cox regression multivariate analysis was used to analyze the independent risk factors affecting the survival of patients with TLPD. P<0.05 was considered statistically significant.

Results

All 57 patients were followed up after surgery,with a median follow-up time was 31 months. K-M survival curve analysis showed that the cumulative survival rate was 47.4%.COX regression analysis showed that clinical T stage,lymph node metastasis and vascular cancer plug were independent risk factors affecting the prognosis and survival of TLPD patients(P<0.05).

Conclusion

Clinical T staging,lymph node metastasis and vascular cancer plug are independent risk factors affecting the prognosis and survival of PATIENTS with TLPD. Early preoperative diagnosis,intervention and treatment are expected to improve the prognosis and survival of patients.

图1 57例壶腹周围癌患者行TLPD术预后生存K-M曲线
表1 57例壶腹周围癌患者行TLPD术预后生存单因素分析[例(%)]
表2 TLPD患者预后生存COX回归多因素分析
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