胃癌合并急性消化道大出血是进展期胃癌的危重急症之一。术前应在保证患者生命体征的情况下经消化内科、外科、药学、放射介入科和重症医学科等多学科会诊全面评估肿瘤分期和可切除性。内镜检查是胃癌合并急性大出血的主要确诊手段及重要治疗方式。外科手术是非手术疗法效果不佳或失败后的唯一补救方法，手术方式应根据肿瘤位置，分期适当选择，联合多脏器切除的扩大根治术对患者的收益值得进一步探索和积累经验。

Gastric cancer with acute hemorrhage is one of the criticalhallenging emergency of advanced gastric cancer. Preoperative Tumor staging and resectability should be fully evaluated by mMulti-disciplinary discussions including Gastroenterology, Surgery, Pharmacy, Radiological Intervention and Intensive care Medicine before surgery should be conducted to comprehensively evaluate tumor staging and resectability under the condition of ensuring the patient's vital signs.to ensure the patient's vital signs. Endoscopy is effective in diagnosing and treating of gastric cancer with acute massive hemorrhage. Surgical surgery is the only remedy for poor or failed non-surgical therapy, and Some patients required surgical treatment when it was impossible to achieve hemostasis by pharmacotherapy and endoscopy or if rebleeding occurred where the conservative treatment had failed, surgical treatment should be appropriate selected base on the location of tumor and staging. The benefits of extended radical mastectomy combined with multiple organ resection are worth further exploration and experience.