切换至 "中华医学电子期刊资源库"

中华普外科手术学杂志(电子版) ›› 2019, Vol. 13 ›› Issue (03) : 317 -319. doi: 10.3877/cma.j.issn.1674-3946.2019.03.032

所属专题: 文献

论著

复发性肝胆管结石腹腔镜和开腹术后肝功能和预后效果比较
刘涛1, 李晓勇1,(), 高永涛1   
  1. 1. 716000 延安,延安大学附属医院普外科
  • 收稿日期:2018-07-05 出版日期:2019-06-26
  • 通信作者: 李晓勇

Comparison of laparoscopic and open surgery on postoperative liver function and prognosis in the treatment of recurrent hepatolithiasis

Tao Liu1, Xiaoyong Li1,(), Yongtao Gao1   

  1. 1. Department of General Surgery, Affiliated Hospital of Yan’an University, Yan’an 716000, China
  • Received:2018-07-05 Published:2019-06-26
  • Corresponding author: Xiaoyong Li
  • About author:
    Corresponding author: Li Xiaoyong, Email:
引用本文:

刘涛, 李晓勇, 高永涛. 复发性肝胆管结石腹腔镜和开腹术后肝功能和预后效果比较[J/OL]. 中华普外科手术学杂志(电子版), 2019, 13(03): 317-319.

Tao Liu, Xiaoyong Li, Yongtao Gao. Comparison of laparoscopic and open surgery on postoperative liver function and prognosis in the treatment of recurrent hepatolithiasis[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(03): 317-319.

目的

比较腹腔镜和开腹手术对复发性肝胆管结石患者术后肝功能和预后的影响。

方法

回顾性分析2013年1月至2017年12月67例有胆道手术史的复发性肝胆管结石患者资料,根据不同术式将患者分为腔镜组(35例)和开腹组(32例)。运用SPSS20.0软件进行统计学分析,手术相关指标等计量资料以(±s)表示,独立t检验;术后并发症发生率采用χ2检验,以P<0.05为差异有统计学意义。

结果

腔镜组手术时间长于开腹组,而术中出血量、术后住院时间和肝功能恢复时间均少于开腹组,两组差异均有统计学意义(P<0.05);两组ALT、AST、TBIL平均水平较术前均下降(P<0.05),且两组间比较无统计学差异(P>0.05)。腔镜组术后并发症发生率为8.6%,显著低于开腹组的31.3%,差异有统计学意义(P<0.05)。

结论

腹腔镜肝切除联合胆道镜用于治疗复发性肝胆管结石安全可靠,值得临床进行推广与应用。

Objective

To compare the effect of laparoscopic hepatectomy combined with choledochoscopy and open surgery on postoperative liver function and prognosis in patients with recurrent hepatolithiasis.

Methods

67 cases of patients who had a history of biliary surgery with recurrent hepatolithiasis from January 2013 to December 2017 were selected as the observation objects. They were divided into laparoscopic group (35 cases received laparoscopic surgery) and open group (32 cases received open surgery) according to the different operation methods. Research data were analyzed by SPSS 20.0 software. The measurement data were expressed as (±s) and were compared by t test while other enumeration data such as incidence of postoperative complications were compared by chi square test. P<0.05 was regarded to be statistically significant.

Results

The operation time in laparoscopic group was longer (P<0.05), the intraoperative blood loss, the length of hospitalization and the recovery time of liver function in laparoscopic group were less than those of open group (P<0.05). The mean levels of ALT, AST and TBIL in both groups were lower than those of before operation (P<0.05), and there was no statistical difference between the two groups(P>0.05). The rate of postoperative complications of laparoscopic group was 8.6%, which were less than that of open group 31.3%, and the difference was statistically significant (P<0.05).

Conclusion

Laparoscopic hepatectomy combined with choledochoscopy for hepatolithiasis is safe and reliable, and it deserves promotion and application.

表1 67例有胆道手术史的肝胆管结石患者不同术式两组患者一般临床资料比较(例)
表2 67例有胆道手术史的肝胆管结石患者不同术式两组患者手术相关情况比较(±s)
表3 67例有胆道手术史的肝胆管结石患者不同术式两组患者治疗前后肝功能指标比较(±s)
表4 67例有胆道手术史的肝胆管结石患者不同术式两组患者术后并发症情况比较(例)
[1]
王平,孙北望,谢嘉奋,等. 腹腔镜联合硬质胆道镜治疗复发性肝胆管结石的临床应用[J]. 现代生物医学进展,2015, 15(18):3499-3501,3547.
[2]
郑四鸣,周新华,陆才德,等. 腹腔镜与开放肝切除治疗复发性肝胆管结石的比较研究[J]. 中华普通外科杂志,2017, 32(5):421-424.
[3]
丁俊,张家耀,张勇,等. 腹腔镜联合胆道镜治疗肝内外胆管结石的临床分析[J/CD]. 中华普外科手术学杂志(电子版), 2016, 10(6):477-479.
[4]
林健群,洪建文,杨熙,等. 精准肝切除在肝胆管结石病中的临床应用分析[J]. 腹腔镜外科杂志,2016,21(2):112-115.
[5]
Xiao J, Zhu J, Liu Z, et al. Role of surgical treatment for hepatolithiasis-associated intrahepatic cholangiocarcinoma: A retrospective study in a single institution[J]. J Cancer Res Ther, 2017, 13(5): 756-760.
[6]
刘启,宋福军,张黎. 开腹与腹腔镜左肝外叶切除术治疗肝内胆管结石的效果比较[J]. 中国现代普通外科进展,2016, 19(8):656-657.
[7]
Tan J, Tan Y, Chen F, et al. Endoscopic or laparoscopic approach for hepatolithiasis in the era of endoscopy in China[J]. Surg Endosc, 2015, 29(1): 154-162.
[8]
Pu Q, Zhang C, Huang Z, et al. Reoperation for recurrent hepatolithiasis: laparotomy versus laparoscopy[J]. Surgical Endoscopy, 2017, 31(8): 3098-3105.
[9]
游勤建,袁发秀,宋平. 腹腔镜联合胆道镜与传统开腹手术治疗胆囊结石合并胆总管结石的疗效对比[J]. 河北医学,2016, 22(5):721-724.
[10]
敖劲,曾令雯,蔡争,等. 急性梗阻性化脓性胆管炎经皮肝穿刺胆道引流术后死亡原因分析[J]. 中国普通外科杂志,2015, 24(8):1195-1197.
[11]
陈永标,池小斌,江艺,等. 腹腔镜肝切除联合胆道镜治疗肝内外胆管结石36例[J]. 中国微创外科杂志,2016, 16(9):777-779.
[12]
李越华,魏东,王琨,等. 腹腔镜与开腹左肝外叶切除联合胆道镜取石治疗左肝内胆管结石的疗效比较[J]. 中国普通外科杂志,2015, 24(8):1070-1076.
[13]
李忠,左旭辉,肖越华,等. 三镜(腹腔镜、胆道镜、十二指肠镜)联合治疗复杂性肝内外胆管结石的研究[J]. 肝胆外科杂志,2015, 23(1):46-48.
[1] 燕速, 霍博文. 腹腔镜食管胃结合部腺癌根治性切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 13-13.
[2] 母德安, 李凯, 张志远, 张伟. 超微创器械辅助单孔腹腔镜下脾部分切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 14-14.
[3] 李国新, 陈新华. 全腹腔镜下全胃切除术食管空肠吻合的临床研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 1-4.
[4] 李子禹, 卢信星, 李双喜, 陕飞. 食管胃结合部腺癌腹腔镜手术重建方式的选择[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 5-8.
[5] 李乐平, 张荣华, 商亮. 腹腔镜食管胃结合部腺癌根治淋巴结清扫策略[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 9-12.
[6] 陈方鹏, 杨大伟, 金从稳. 腹腔镜近端胃癌切除术联合改良食管胃吻合术重建His角对术后反流性食管炎的效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 15-18.
[7] 许杰, 李亚俊, 韩军伟. 两种入路下腹腔镜根治性全胃切除术治疗超重胃癌的效果比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 19-22.
[8] 李刘庆, 陈小翔, 吕成余. 全腹腔镜与腹腔镜辅助远端胃癌根治术治疗进展期胃癌的近中期随访比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 23-26.
[9] 刘世君, 马杰, 师鲁静. 胃癌完整系膜切除术+标准D2根治术治疗进展期胃癌的近中期随访研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 27-30.
[10] 王庆亮, 党兮, 师凯, 刘波. 腹腔镜联合胆道子镜经胆囊管胆总管探查取石术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 313-313.
[11] 杨建辉, 段文斌, 马忠志, 卿宇豪. 腹腔镜下脾部分切除术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 314-314.
[12] 叶劲松, 刘驳强, 柳胜君, 吴浩然. 腹腔镜肝Ⅶ+Ⅷ段背侧段切除[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 315-315.
[13] 郭兵, 王万里, 何凯, 黄汉生. 腹腔镜下肝门部胆管癌根治术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 143-143.
[14] 李凯, 陈淋, 苏怀东, 向涵, 张伟. 超微创器械在改良单孔腹腔镜巨大肝囊肿开窗引流及胆囊切除中的应用[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 144-144.
[15] 魏丽霞, 张安澜, 周宝勇, 李明. 腹腔镜下Ⅲb型肝门部胆管癌根治术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 145-145.
阅读次数
全文


摘要