Abstract:
Objective To compare the safety and long-term follow-up evaluation of natural ori?ce specimen extraction surgery（NOSES）and hybrid minimally invasive/open approach（HMOA）.
Methods 122 patients with rectal cancer treated between June 2013 and September 2015 were analyzed retrospectively，which were divided into two groups according to different surgical procedures，namely the NOSES group（n=64 cases）and HMOA group（n=58 cases）. SPSS 23.0 statistical software was used to analyze the data. The measurement data，such as surgery-related indicators，were expressed as（
±
s）and compared by independent sample
t test. Postoperative complications and recurrence rate，were compared by
χ2 test. The cumulative survival rate was tested by
Log-Rank test.
P<0.05 was statistically significant.
Results The operation time in the NOSES group was longer than that in the HMOA group，and the postoperative exhaust time and hospital stay were shorter than those in the HMOA group（P<0.05）；There were no significant differences in intraoperative blood loss，number of lymph node dissections，3-year or 5-year survival rate and the recurrence rate between two groups（P>0.05）；the total incidence of complications in the NOSE group was lower than that in the HMOA group（10.9% vs. 25.9%）（P<0.05）.
Conclusion Compared with HMOA，NOSES is a more obvious minimally invasive，with lower risk of postoperative complications and faster postoperative recovery，but there is no significant difference in long-term recurrence rate and survival rate between the two surgical methods.
Key words:
Rectal neoplasms,
Natural orifice specimen extraction surgery,
Hybrid minimally invasive/open approach,
Postoperative complications,
Survival status
Junfeng Hao, Hongxia Wei, Kai Lei. Mid-and long-term follow-up comparison of two surgical methods for rectal cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(04): 462-464.