Abstract:
Objective To compare the efficacy and prognosis of three kinds of operation for stage Ⅰ-Ⅱ breast cancer.
Methods The data of 127 patients with breast cancer who underwent surgical treatment from March 2013 to March 2018 were retrospectively analyzed. They were divided into three groups according to the operation types：endoscopic group（40 cases underwent single hole endoscopic breast conserving surgery），traditional group（44 cases underwent traditional open breast conserving surgery），and radical resection group（43 cases underwent open total mastectomy）. SPSS 23.0 statistical analysis software was used，and the operation-related indicators were expressed as（
±
s），and single-factor analysis of variance was used among multiple groups；the count data such as complications and metastasis rate were expressed as rates，and
χ2 test was used for comparison；
P < 0.05 was considered statistically significant.
Results Operation time：traditional group < radical group < endoscopic group（P < 0.05）；Intraoperative bleeding，number of lymph node dissections，length of hospital stay and total incidence of complications：endoscopic group < traditional group < radical group（P < 0.05）；The excellent and good rate of breast beauty：endoscopic group > traditional group > radical mastectomy group（P < 0.05）；There was no significant difference in local recurrence rate and metastasis rate among the three groups（P > 0.05）.
Conclusion Endoscopic breast-conserving surgery，traditional open breast-conserving surgery and modified radical mastectomy have similar efficacy in the treatment of stage Ⅰ to Ⅱ breast cancer，and there is no significant difference in the risk of mid and long term recurrence and metastasis. However，endoscopic breast-conserving surgery has certain advantages in breast aesthetics and postoperative recovery.
Key words:
Breast neoplasms,
Laparoscopes,
Mastectomy，modified radical,
Prognosis,
Comparative effectiveness research
Tuo Han, Wei Zhang, Liang Chen, Dong Xiao. Comparison of the curative effect and prognosis of three surgical methods in the treatment of stage Ⅰ-Ⅱ breast cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(02): 150-153.