To evaluate the short-term and long-term efficacy and aesthetic effect of modified radical mastectomy with modified mastectomy assisted by mastectomy and prosthesis implantation in stage Ⅰ for early breast cancer.

Retrospective analysis of 64 patients underwent modified radical mastectomy for early breast cancer from January 2016 to December 2016，The patients were divided into breast conserving group（n=32）and radical mastectomy group（n=32）according to their wishes. The breast conserving group was treated with modified radical mastectomy with nipple retention and areola complex assisted by mammoscopy，and the prosthesis was implanted into one-stage plastic surgery. The radical mastectomy group was treated with traditional open modified radical mastectomy. SPSS 19.0 software was used for analysis，perioperative indicators and FACT-B score are expressed as（

The operation time of breast conserving group was longer than that of radical mastectomy group（P<0.05）；There was no significant difference in the incidence of complications，survival rate at 12 and 36 months，recurrence rate and metastasis rate between the two groups（P>0.05）. The subjective satisfaction rate of breast conserving group was 65.6%，the objective excellent and good rate was 81.3%，and the radical cure group was 12.5% and 21.9%，respectively. The difference was statistically significant（P<0.05）. The scores of social state，emotional state，functional state，additional attention state and total score in the breast conserving group were higher than those in the radical cure group（P<0.05）.

Mastoscope-assisted breast-conserving modified radical mastectomy combined with implantation of prosthesis stage Ⅰ for the treatment of early breast cancer can ensure the curative effect and also have cosmetic effects，which can significantly improve the quality of life of patients.