Abstract:
Objective To investigate short-term clinical outcome of laparoscopic sleeve gastrectomy in treating obesity combined with type 2 diabetes mellitus.
Methods From June 2016 to December 2018, clinical data of 58 patients with both obesity and type 2 diabetes were analyzed retrospectively, including 27 patients underwent laparoscopic sleeve gastrectomy were divided into LSG group, while 31 patients underwent laparoscopic gastric bypass were divided into LRYGB group. Statistical analysis were performed by using SPSS24.0 software. Measurement data such as Perioperative indexes、glucose and lipid metabolism indexes were expressed as (±s) and were examined by using Independent sample t test. Count data such as complication rate、clinical outcome were expressed as %, and were examined by using χ2. A P value of <0.05 was considered as statistically significant.difference.
Results All of 58 patients underwent successful laparoscopic surgery. The operation time in LSG group was significantly shorter than that in LRYGB group (P<0.05). At 3 months and 6 months postoperatively, BMI, glucose metabolism index and lipid metabolism index of the patients in the two groups decreased significantly than before (P<0.05), while there were no significant changes in terms of serum albumin (P>0.05). But there was no statistically significant difference between the two groups postoperatively (P>0.05). The clinical complete response rate for type 2 diabetes was 77.8% in the LSG group and 74.2% in the LRYGB group, with similar therapeutic effects in two groups for type 2 diabetes (P>0.05).
Conclusion LSG is safe and effective as an independent weight loss operation, and is effective for obese patients with type 2 diabetes in the early stage, which is worthy of clinical promotion.
Key words:
Diabetes mellitus, type 2,
Obesity,
Laparoscopes,
Comparative effectiveness research
Wenming Liu, Liangtao Luo, Shaoxiang Cao, Yonghong Li, Xiangyuan Yan. Short-term clinical outcome of laparoscopic sleeve gastrectomy in treating obesity combined with type 2 diabetes mellitus[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(01): 69-72.