Abstract:
Objective To investigate the effects of 3D reconstruction technology combined with laparoscopic precision hepatectomy on the levels of CD4+, CD8+ and immunoglobulin in patients with liver cancer after surgery.
Methods The clinical data of 384 patients with liver cancer from April 2021 to March 2023 were retrospectively analyzed and divided into two groups according to surgical methods, 192 patients in each group. The control group was treated with laparoscopic precision hepatectomy, and the observation group was treated with three-dimensional reconstruction technology combined with laparoscopic precision hepatectomy. SPSS 26.0 software was used to analyze the data. Clinical efficacy, incidence of adverse reactions and other statistical data were expressed by [cases (%)] and χ2 test was performed. Measurement data such as CD4+, CD8+ and immunoglobulin levels were expressed by (
), and independent sample t test was performed. P<0.05 was considered statistically significant.
Results Compared with the control group, the operation time and the first time of getting out of bed after operation in the observation group were shorter (P<0.05), and the amount of blood loss during operation was less (P<0.05). After operation, the serum alpha-fetoprotein (AFP) level of both groups was decreased (P<0.05), and the observation group was lower than the control group (P<0.05). After surgery, the levels of CD4+, IgM and IgG were all decreased (P<0.05), while the levels of CD8+ and IgA were not significantly different compared with those before surgery (P>0.05). The levels of CD4+, CD8+ and immunoglobulin in observation group were not significantly different from those in control group (P>0.05). The total complication rate of observation group was lower than that of control group (P<0.05). There were no significant differences in the recurrence rate and mortality of tumor in observation group and control group at 1 year after surgery (P>0.05).
Conclusion 3D reconstruction combined with laparoscopic precision hepatectomy did not reduce the effects on the levels of CD4+, CD8+ and immunoglobulin in patients with liver cancer after surgery, but could reduce the occurrence of complications.
Key words:
Liver Neoplasms,
Laparoscopes,
Hepatectomy,
Imaging, Three-Dimensional,
CD4-Positive T-Lymphocytes,
CD8-Positive T-Lymphocytes,
Immunoglobulin G
Quanyou Lai, Yuan Gao, Jianlin Wang, Shibin Qu, Dan Wei, Wei Peng. Effects of 3D reconstruction technology combined with laparoscopic precision hepatectomy on the levels of CD4+, CD8+ and immunoglobulin in patients with liver cancer after surgery[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2024, 18(06): 651-654.