To investigate the clinical safety and feasibility of modified laparoscopic splenectomy+ pericardial devascularization (LSPD) in the treatment of cirrhosis complicated with portal hypertension.

A retrospective study was conducted in 163 patients with cirrhosis complicated with portal hypertension, including esophagogastric varices and hypersplenism who underwent LSPD from March 2015 to April 2019. According to the operation method, the patients were divided into the conventional group (68 cases of routine LSPD surgery) and the modified group (85 cases of modified LSPD surgery). Statistical analysis were performed by using SPSS21.0 software. Measurement data such as perioperative indicators were expressed as (±s) and were analyzed by using independent sample t test. χ²/Fisher test was used to examined the complication rate and the rate of conversion to laparotomy. A P value of <0.05 was considered as statistically significant difference.

There were 4 cases of conversion to laparotomy in the conventional group, while 1 case in the modified group. The modified group was significantly better than the conventional group in terms of operation time, intraoperative bleeding, postoperative recovery index and complications rate (P<0.05). Total postoperative complications incidence of 14.1% in the modified group was significantly lower than 27.9% in the conventional group (χ²=6.276, P=0.012).

Modified LSPD is safe and feasible for patients with cirrhosis complicated with portal hypertension, which has significant advantages in terms of shorter operation time, less bleeding and faster postoperative recovery, and could also improve the therapeutic effect of patients with giant spleen, which is worthy of clinical promotion.