Abstract:
Objective To explore the efficacy and safety of laparoscopic resection of gastrointestinal stromal tumor.
Methods Data of 80 patients who underwent gastrointestinal stromal tumor resection from March 2014 to July 2017 were retrospectively analyzed, they were divided into laparoscopic group (62 cases) and laparotomy group (18 cases) according to different surgical methods. Statistical software SPSS21.0 was used for data analysis, perioperative indicators were represented by (±s), and independent sample t test was used. The incidence of postoperative complications was compared by χ2. Kaplan-meier method was used for prognosis and survival analysis, with P<0.05 as the test standard.
Results The laparoscopic group was better than the laparotomy group in terms of operation time, blood loss and postoperative recovery (P<0.05). There was no significant difference in the overall incidence of postoperative complications, disease-free survival rate at 20 months after surgery and overall survival rate between the two groups (P>0.05). Histopathological examination showed that the lesions of gastrointestinal stromal tumor were mostly oval, almost round and irregular, among which spindle cell type accounted for the largest proportion (71.3%). Immunohistochemistry showed that the positive rate of CD34 protein was 83.7%, that of CD117 protein was 95.0%, and that of DOG1 protein was 91.3%.
Conclusion Laparoscopic resection of gastrointestinal stromal tumor is shorter, less bleeding, faster recovery and less complications than traditional laparotomy.
Key words:
Gastrointestinal stromal tumor,
Laparoscopes,
Surgical procedures, operative,
Treatment outcome,
Safety
Gang Yin, Zhipeng Sun, Peirong Tian, A min bu he, Tianxiong Li. Single-center retrospective analysis of laparoscopic resection of gastrointestinal stromal tumor[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(01): 70-73.