To investigate the safety and feasibility of laparoscopic pancreaticoduodenectomy via uncinate approach.

From January 2014 to June 2016, Clinical data of 76 patients who underwent pancreaticoduodenectomy were analyzed retrospectively, including 36 patients in open group and 30 patients in LPD group according to surgical treatments. Statistical analysis were performed by using SPSS 22.0 software. Measurement data, such as intraoperative and postoperative indicators were expressed as(±s), and were examined by using independent t test. Count data such as postoperative complications were examined by chi square test and Fisher’s exact probability method. A P value <0.05 was considered as statistically significant difference.

Pathological results showed that the R0 resection rate was 100% in both groups. The operation time, intraoperative blood loss, ambulation time, the first eating time and length of hospital stay in the LPD group were better than those in the open group respectively(P<0.05). There was no significant difference between the two groups in terms of incidence of postoperative complications such as pancreatic fistula, gastric emptying disorder, biliary fistula, postoperative bleeding, and postoperative infection(P>0.05). There was no significant difference between the two groups in terms of 3-year overall survival rate (26.67% vs. 36.67%) (χ²=3.014, P>0.05).

Laparoscopic pancreaticoduodenectomy via uncinate approach has advantages such as less bleeding, quick recovery and is safe and feasible.