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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2019, Vol. 13 ›› Issue (03): 287-289. doi: 10.3877/cma.j.issn.1674-3946.2019.03.023

Special Issue:

• Original Article • Previous Articles     Next Articles

Comparison of clinical efficacy and cellular immune status of different surgical methods in the treatment of elderly patients with colon cancer

Chaoyun Su1,(), Qinzhong Wei1, Gang Wang1, Yi Ren1, Wen Guo1   

  1. 1. Beijing aerospace general hospital Beijing 100076
  • Received:2018-07-01 Online:2019-06-26 Published:2019-06-26
  • Contact: Chaoyun Su
  • About author:
    Corresponding author: Su Chaoyun, Email:

Abstract:

Objective

To compare the clinical efficacy and cellular immune status of laparoscopy and laparotomy in the treatment of elderly patients with colon cancer.

Methods

Clinical data of 103 elderly patients with colon cancer from August 2014 to December 2017 treated in our hospital were selected, and the patients were divided into laparoscopic group (52 cases) and laparotomy group (51 cases) according to the different methods. The incidence of complications, cellular immune function, and prognosis were compared between the two groups.

Results

The incidence of complications in laparoscopic group was significantly lower than that in laparotomy group, the differences were statistically significant (P<0.05); After treatment, CD3, CD4, and CD4/CD8 in both groups were lower than before (P<0.05), and CD8 was higher than before (P<0.05), and CD3, CD4, CD4/CD8 in laparoscopic group were higher than those in laparotomy group (P<0.05), CD8 in laparoscopic group was lower than that in the laparotomy group (P<0.05); Compared with the laparotomy group, patients in the laparoscopic group had shorter postoperative analgesics, more rapid recovery of gastrointestinal function, earlier fluid intake time, earlier ambulation, shorter indwelling catheterization time, and shorter hospitalization time (all P<0.05).

Conclusion

Compared with traditional laparotomy surgery, laparoscopic radical resection of colon cancer can effectively reduce the incidence of complications, it has little effect on patient’s cellular immune function, it can shorten the recovery time of the postoperative gastrointestinal function, ambulation activity time and hospitalization time, it is beneficial to the prognosis of patients and is consistent with the concept of rapid recovery surgery, it is worthy of promotion and application.

Key words: Colonic neoplasms, Aged, Laparoscopes, Immunity, cellular, Prognosis

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