Clinical application of metabolic surgery in the treatment of obesity with type 2 diabetes mellitus

doi:10.3877/cma.j.issn.1674-3946.2019.01.033

Abstract

Abstract:

As the prevalence rate of obesity with type 2 diabetes mellitus continues to rise and the rapid development of metabolic surgery, more and more evidences prove that metabolic surgery can significantly improve the blood sugar in the cases of obesity with type 2 diabetes. More and more scholars explore the mechanism of metabolic surgery how to improve blood sugar. And clinical experiences also reveal the different possible mechanisms, the curative effect and security of the metabolic surgery are accepted by a lot of physicians and surgeons. In order to control the postoperative blood glucose of patients, the diet health of education after metabolic surgery is also noticed by some scholars. The purpose of this paper is to analyze the mechanism of metabolic surgery to treat obesity combined with type 2 diabetes mellitus, the progress of clinical efficacy and postoperative management, so as to provide a basis for the diagnosis, treatment and prognosis of obese patients with type 2 diabetes mellitus.

Key words: Obesity, Diabetes mellitus, type 2, Laparoscopes, Metabolism

YanHai, Aili Aikebaier. Clinical application of metabolic surgery in the treatment of obesity with type 2 diabetes mellitus[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(01): 105-108.

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References 31

[1]	Pories WJ，Swanson MS，Macdonald KG，et al.Who would have thought it? An operation proves to be the most effective therapy for adult－onset diabetes mellitus[J]．Ann Surg，1995，222(3):339-350.
[2]	Benedix F，Meyer F，Klose S，et al.Is there a role for surgery in the treatment of type 2 diabetes？[J]．Dtsch Med Wochenschr，2014，139(5):207-212.
[3]	Rubino F，Nathan DM，Eckel RH，et al.Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations[J]．Diabetes Care，2016，39(6):861-877.
[4]	刘金钢，郑成竹，王勇，等．中国肥胖和2型糖尿病外科治疗指南(2014版)[J]．中国实用外科杂志，2014，34(11):1005-1006.
[5]	Chen Z．Adapter proteins regulate insulin resistance and lipid metabolism in obesity[J]．Science Bulletin，2016，61(19):1489-1497.
[6]	Ren ZQ，Zhang PB，Zhang XZ，et al.Duodenal－jejunal exclusion improves insulin resistance in type 2 diabetic rats by upregulating the hepatic insulin signaling pathway[J]．Nutrition，2015，31(5):733-739.
[7]	Sadi G，Ergin V，Yilmaz G，et al.High－fructose corn syrup－induced hepatic dysfunction in rats: improving effect of resveratrol[J]．Eur J Nutr，2015，54(6):895-904.
[8]	Abu Dayyeh BK, Jirapinyo P, Thompson CC.Plasma Ghrelin Levels and Weight Regain After Roux－en－Y Gastric Bypass Surgery[J]．Obes Surg，2017，27(4):1031-1036.
[9]	Tasyurek HM, Altunbas HA, Balci MK，et al.Incretins: their physiology and application in the treatment of diabetes mellitus[J]．Diabetes metab Res Rev，2014，30(5):354-371.
[10]	Tharakan G，Behary P，Wewer Albrechtsen NJ，et al.Roles of increased glycaemic variability, GLP－1 and glucagon in hypoglycaemia after Roux－en－Y gastric bypass[J]．Eur J Endocrinol，2017，177(6):455-464.
[11]	Calanna S，Christensen M，Holst JJ，et al.Secretion of glucagon－like peptide－1 in patients with type 2 diabetes mellitus: systematic review and meta－analyses of clinical studies[J]．Diabetologia，2013，56(5):965-972.
[12]	彭涛，何劲松，魏寿江．外科治疗2型糖尿病的主要手术方式与机制[J]．川北医学院学报，2014，29(1):101-106.
[13]	秦凤．肥胖性2型糖尿病患者的微创袖状胃切除手术效果[J]．世界华人消化杂志，2015，23(28):4595-4601.
[14]	Greve JWM.Chapter 35－Bariatric Surgery Improves Type 2 Diabetes Mellitus[J]．Metabolism and Pathophysiology of Bariatric Surgery，2017：315-323.
[15]	Walicka M，Chomiuk T，Filipiak K，et al.Type 2 diabetes prevention. Experts’ Group position paper endorsed by the Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy[J]．Kardiol Pol，2015，73(10):949-957.
[16]	Mahdi T，Hanzelmann S，Salehi A, et al.Secreted frizzled－related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes[J]．Cell Metab，2012，16(5):625-633.
[17]	Liu F，Qu H，Li Y，et al.Relationship between serum secreted frizzled－related protein 4 levels and the first－phase of glucose－stimulated insulin secretion in individuals with different glucose tolerance[J]．Endocr J，2015，62(8):733-740.
[18]	Anand K，Vidyasagar S，Lasrado I，et al.Secreted Frizzled－Related Protein 4 (SFRP4): A Novel Biomarker of β－Cell Dysfunction and Insulin Resistance in Individuals With Prediabetes and Type 2 Diabetes[J]．Diabetes Care，2016，39(9):e147-e148.
[19]	任彦红，黄婷，栗夏连．不同糖耐量人群血浆分泌型卷曲相关蛋白4水平与糖脂代谢、胰岛功能的相关研究[J]．中国实用医刊，2014，41(7):50-52.
[20]	胡兴娜，成兴波．脂肪细胞因子SFRP4在肥胖及2型糖尿病领域的研究进展[J]．江苏医药，2017，43(8):586-588.
[21]	Aminian A，Kirwan J，Burguera B，et al.A Nationwide Safety Analysis of Bariatric Surgery In Nonmorbidly Obese Patients With Type 2 Diabetes[J]. Surgery for Obesity and Related Diseases, 2016，12(6):1163-1170.
[22]	Mingrone G，Panunzi S，De Gaetano A，et al.Bariatric－metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow－up of an open－label, single－centre，randomised controlled trial[J]．Lancet，2015，386(9997):964-973.
[23]	Schauer PR，Bhatt DL，Kirwan JP，et al.Bariatric surgery versus intensive medical therapy for diabetes－3－year outcomes[J]．N Engl J Med，2014，370(21):2002-2013.
[24]	Courcoulas AP，Yanovski SZ，Bonds D，et al.Long－term outcomes of bariatric surgery: a National Institutes of Health symposium[J]．JAMA Surg，2014，149(12):1323-1329.
[25]	Brethauer SA，Aminian A，Romero－Talamás H，et al.Can diabetes be surgically cured? Long－term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus[J]. Ann Surg，2013，258(4):628-637.
[26]	Arterburn DE，Olsen MK，Smith VA，et al.Association between bariatric surgery and long－term survival[J]. JAMA，2015，313(1):62-70.
[27]	常绪生，郑成竹，王鑫，等．腹腔镜袖状胃切除术治疗肥胖性2型糖尿病的疗效分析[J]．中华胃肠外科杂志，2014，17(7):658-662.
[28]	谢静，张伟，单成祥，等．腹腔镜袖状胃切除术治疗病态性肥胖合并2型糖尿病近期疗效分析[J]．现代生物医学进展，2014，14(5):870-872.
[29]	张敬坡，冯雷，秦静，等．腹腔镜胃旁路术和胃袖状切除术治疗肥胖合并2型糖尿病的疗效比较[J]．江苏大学学报(医学版)，2016，26(1):49-53.
[30]	邹雪琴，姜敏．腹腔镜可调胃束带手术联合艾塞那肽治疗肥胖型2型糖尿病临床疗效分析[J]．中国全科医学，2017，20(35):4433-4437.
[31]	丁丹，郑成竹．胃肠外科手术治疗2型糖尿病的质量控制及管理[J]．外科理论与实践，2015，20(5):369-371.

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