To investigate the protective effect of nano carbon on parathyroid gland and recurrent laryngeal nerve in papillary thyroid micro-carcinoma surgery.

A total of 67 patients with papillary thyroid micro-carcinoma from June 2015 to May 2017 were enrolled into this study. 67 patients, who were randomly divided into nanometer carbon group (n=33) and routine operation group (n=34). The changes of parathyroid hormone, serum calcium level and postoperative complications were observed in both χ² groups. Statistical analysis were performed by using SPSS 19.0 software. Perioperative measurement data, such as parathyroid hormones and serum calcium levels were expressed as (±s), and were examined by using t test.The postoperative complication rate was analyzed by Chi-square test. A P value <0.05 was considered as statistically significant difference.

The intraoperative blood loss, operation time, recovery and discharge time and parathyroid miscut rate were significantly lower in nano-carbon group than those in routine operation group (P<0.05), and the Number of lymph node dissection in VI region of two groups was lower than that in conventional operation group. There was no significant difference in lymph node metastasis between two groups (P>0.05), there was no significant difference in terms of serum calcium and parathyroid hormone levels between two groups before operation (P>0.05), and within 3 days after operation, parathyroid hormone was found in the nano-carbon group. The level of serum calcium in routine operation group was significantly higher than that in routine operation group (P<0.05), and gradually recovered in routine operation group 7 days after operation, and there was no difference compared with nano-carbon group (P>0.05). The incidence of postoperative complications such as hoarseness, spontaneous voice weakness and transient hypocalcemia in the carbon group was significantly lower than those in the routine operation group (P<0.05). The recurrence rate of tumor focus in nano-carbon group was lower than that in conventional operation group 3 and 6 months after operation, with no significant difference (P>0.05).

Nano carbon could be used to distinguish parathyroid gland and lymph node clearly in thyroid micropapillary carcinoma surgery. It is important to protect parathyroid gland and surrounding normal tissue and is worth popularizing.