Compare the short-term efficacy and quality of life between laparoscopic proximal gastrectomy (LPG) esophagogastrostomy (EG) with vagal nerve transection and H-M pyloroplasty and modified pyloric myotomy.

A total of 66 patients with LPG proximal gastric cancer (PGC) admitted to our hospital from January 2020 to June 2022 were selected as research objects. The patients were divided into the improved group and the traditional group according to random number table,each of 33 cases. Esophagogastric stump anastomosis and vagus nerve dissection were used in both groups. MP was added in the improved group and HMP was added in the traditional group. The data were processed by SPSS 22.0 software. Perioperative indicators, postoperative quality of life and other measurement data were expressed by (), and independent t-test was performed. Statistical data such as postoperative complications were represented by [n (%)] and χ² test was performed. P<0.05 was considered statistically significant.

There were no significant differences in operation time, intraoperative blood loss, intestinal function recovery time, indindent time of gastric tube, postoperative hospital stay and postoperative GCSI score between the two groups (P>0.05). There were no significant differences in postoperative abdominal infection, anastomotic leakage, anastomotic hemorrhage, gastric emptydisorder and long-term complications such as anastomotic stenosis, pyloric stenosis and gastric retention between the two groups (P>0.05). However, the incidence of postoperative bile reflux in the improved group was significantly lower than that in the traditional group (6.7%vs.30.3%, P<0.05). During the follow-up period, the total score of the gastroesophageal reflux scale (Gerd Q) in the improved group was significantly lower than that in the traditional group, and the total score of Chew-wun Wu was significantly increased (P<0.05). The scores of dietary quantity, dietary times, abdominal distension and stomach burning sensation in the improved group were significantly higher than those in the traditional group (P<0.05).

Compared with H-M pyloroplasty, modified pyloromyotomy in LPG not only reduces the occurrence of postoperative bile reflux, improves the postoperative gastroesophageal reflux symptoms, but also improves the postoperative quality of life of patients.