The qualitative and quantitative characteristics of contrast-enhanced ultrasound (CEUS) for early breast cancer were compared between benign breast lesions and advanced breast cancer.

A retrospective analysis was performed on the data of 110 patients with benign and malignant breast lesions diagnosed pathologically from December 2018 to February 2020, all of whom underwent breast CEUS examination and surgical treatment during the same period. The patients were grouped according to the size of the lesions and pathological indications: The cases were divided into three groups: 50 cases of benign breast lesions (group A), 21 cases of early breast cancer (group B), and 39 cases of advanced breast cancer (group C). Statistical software SPSS 26.0 was used for statistical processing, and χ² test was used for comparison of qualitative indicators. The quantitative indicators were compared with each other by Nonparametric test. P<0.05 was considered statistically significant.

Comparison of qualitative and quantitative indicators between early breast cancer and benign breast lesions showed that early breast cancer was mainly characterized by high enhancement of fast advance/slow regression, and the scope expanded significantly after perfusion, with high peak intensity and short peak time, and the difference was statistically significant (P<0.05). Compared with advanced breast cancer, high enhancement and isoenhancement were more common in early breast cancer, contrast agent distribution was uniform, perfusion defect was rare, peak intensity was slightly lower than that of advanced breast cancer, and peak time was slightly longer, the difference between the two was statistically significant (P<0.05).

The qualitative and quantitative indicators of contrast-enhanced ultrasound have certain characteristics, which can provide reference value and help for the accurate diagnosis of early breast cancer.