Abstract:
Objective To investigate the effect of rapid rehabilitation surgery (FTS) on postoperative gastrointestinal function, inflammatory response and nutritional indicators in stage Ⅲ colon cancer patients.
Methods F 67 patients with stage Ⅲ colon cancer were selected from January 2018 to December 2020. According to different perioperative treatments, patients were divided into FTS group (n=33) and traditional group (n=34) by random number table method. Patients in the FTS group were treated with FTS perioperative treatment + laparoscopic radical resection, and patients in the traditional group were treated with traditional perioperative treatment + laparoscopic radical resection. SPSS 21.0 software was used for comparison. Postoperative gastrointestinal function recovery index, inflammatory response index and nutrition index were expressed as (±s), independent sample t test was used. χ2 test was used for measurement data, P<0.05 was considered statistically significant.
Results The time of first exhaust and first defecation in FTS group was faster than that in the traditional group (P<0.05). Serum levels of TNF-α, IL-6 and IL-8 in the two groups were higher than those before surgery (P<0.05), but the three inflammatory response indexes of FTS group were lower than those in the traditional group (P<0.05) . The levels of total protein, prealbumin and albumin at 3 days after operation were lower than those before operation (P<0.05), but the nutritional indexes in the FTS group were higher than those in the traditional group (P<0.05).
Conclusion Rapid rehabilitation surgery can promote gastrointestinal function recovery, reduce inflammation and improve nutritional status of stage Ⅲ colon cancer patients.
Key words:
Colonic neoplasms,
Inflammation,
Nutritional status,
Gastrointestinal function,
Fast track surgery
Yanna Zhao, Fang Wang, Jie Wu, Jian Xu. The effect of rapid rehabilitation surgery on gastrointestinal function, inflammatory reaction and nutritional indicators in patients with stage Ⅲ colon cancer after operation[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(06): 633-635.