Abstract:
Objective To investigate the clinical effect of laparoscopic D3 radical resection of right hemicolonic carcinoma plus subpyloric and gastroepiploic lymph node (IGLN) dissection in the treatment of locally advanced hepatocolon carcinoma.
Methods The data of 60 patients with locally advanced hepatocellular carcinoma from May 2018 to October 2023 were retrospectively analyzed. The patients were divided into observation group and control group according to the different scope of lymph node dissection, 30 patients in each group. The control group underwent laparoscopic D3 radical resection of right hemicoloma carcinoma, and the observation group underwent D3 radical resection of right hemicoloma carcinoma combined with IGLN dissection. Statistical software SPSS 22.0 was used to analyze the data. Perioperative indicators and other measurement data were expressed with (
), and independent sample t test was performed. Complications and other statistical data were represented by [cases (%)] using χ2 test or Fisher exact probability method. Kaplan-Meier method was used to analyze the prognosis and survival. P<0.05 indicated that the difference was statistically significant.
Results There were no significant differences in operation time, intraoperative blood loss, number of lymph dissection, first exhaust time and hospital stay between the two groups (P>0.05). A total of 480 IGLN lymph nodes were obtained, of which the positive rate of IGLN was 15.4%. The total complications in the observation group were higher than those in the control group, but the difference was not statistically significant (P>0.05), and all patients were cured after conservative treatment. Kaplan-Meier survival analysis showed that 5-year cumulative overall survival and disease-free survival (76.7% and 66.7%) in the observation group were significantly higher than those in the control group (53.3% and 46.7%), and the difference was statistically significant (P<0.05).
Conclusion Intraoperative application of D3 radical resection of right half colon cancer combined with IGLN dissection in the treatment of locally advanced hepatocolon carcinoma can improve the prognosis and survival of patients, and is safe and feasible, which has the prospect and value of clinical promotion.
Key words:
Colonic Neoplasms,
Laparoscopes,
Infrapyloric and Gastroepiploic Lymph Node,
Lymph Node Excision,
Survival Curve
Hongshuai Cui, Liming Feng, Weiling Dong, Bo Han. The clinical effect of laparoscopic D3 radical resection of right half colon cancer plus IGLN dissection in the treatment of locally advanced hepatocolon carcinoma[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2024, 18(05): 566-569.