To evaluate the clinical outcome of intermuscular and interthroat approaches in the reoperation of thyroid cancer.

From July 2017 to June 2019, a retrospective analysis were performed in 81 patients who underwent reoperation for thyroid cancer. According to the operation procedures, 43 patients who treated with traditional central thyroidectomy were divided into the traditional group, while38 patients who treated with central thyroidectomy with intermuscular and interthroat approaches were divided into the improved group. Statistical software SPSS24.0 were used for data analysis. Measurement data such as Perioperative indexes were represented as (±s), and were examined by independent t test. Chi-square test were performed for count data analysis such as complication rate. P<0.05 was considered as statistically significant difference.

There were no significant difference between the Improved group and the traditional group in terms of the perioperative indexes, such as the operation time, the amount of bleeding during the operation, the postoperative hospital stay and the recovery level of parathyroid hormone on the first day after the operation (P>0.05). There was no statistically significant difference between the Improved group and the traditional group in terms of postoperative complications such as hoarseness, water choking, dysphagia and hypocalcemia (P>0.05). Postoperative followed-up of 4-22 months were performed (with average of 11.6 months ). During the follow-up period, there was no death or recurrence in both groups. The parathyroid hormone of all patients gradually returned to normal 1-3 months after operation, and there was no permanent hypoparathyroidism or permanent recurrent laryngeal nerve injury.

In the reoperation of thyroid cancer, it is safe and feasible to operate in the dorsal area of thyroid gland through intermuscular and interthroat approaches, and the clinical outcome is satisfactory, which is worth recommending in clinical practice.