To compare the short-term clinical efficacy of laparoscopic resection(LR), open resection(OR) and radiofrequency ablation under ultrasound localization for hepatocellular carcinoma(RFA).

The data of 152 patients with hepatocellular carcinoma who underwent surgery in our hospital from June 2010 to June 2018 were retrospectively analyzed.71 patients who were treated with laparoscopic resection (LR) were included in the LR group, 52 patients who were treated with open resection (OR) were included in the OR group, and 29 patients who were treated with ultrasound-localized radiofrequency ablation (RFA) were included in the RFA group.SPSS 25.0 software package was used to verify the entire group of data. Measurement data such as surgery-related indicators and VAS scores were described by (±s) and t tests were performed. Frequency (n) and rate (%) were used for counting data such as recent efficacy and complications. Description, χ² test was performed, and comparison among multiple groups was performed by one-way analysis of variance. P<0.05 was considered statistically significant.

Comparing the total effective rate of three groups of patients 3 months after operation, LR group (76.1%) > OR group (73.1%) > RFA group (72.4%), but the difference was not statistically significant (P>0.05); The operation time, total bleeding volume and hospitalization time of the three groups were compared, the OR group > Lr Group > RFA group (P<0.05) ; The Vas scores after 24 hours and 1 week after operation were compared, the overall incidence of complications in the OR group (36.5%) > LR group (29.6%) > RFA group (6.7%)(P<0.05) ; The comparison of the recurrence rate after 3 months of follow-up, OR group (7.7%) <LR group (8.5%) <RFA group (10.3%) (P>0.05).

For patients with hepatocellular carcinoma with early stage and small tumors treated with LR, OR, and RFA, the recent treatment results are comparable, but compared with LR and OR, RFA has less damage and faster postoperative recovery Advantages can reduce the degree of postoperative pain and higher safety. However, for patients with hepatocellular carcinoma with large tumors and close to important vascular bile ducts, individualized treatment is still needed.