Abstract:
Objective To investigate the efficacy of different surgical methods in the treatment of early gallbladder carcinoma, and to observe the effect of 5-year survival rate.
Methods The patients with early gallbladder carcinoma (n=84 cases) from January 2011 to February 2014 were selected as the experimental subjects. According to the random digital table method, the selected patients were divided into two groups, each group was 42 cases, among which the open group was treated by radical cholecystectomy and laparoscopic cholecystectomy was performed in the laparoscopic group. The data were analyzed by SPSS 22.0 statistical software. Among them, the indexes of coagulation function (prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and plasma D-dimer levels) were expressed as (±s), and compared with t test The total effective rate was compared with χ2 test and the effective rate was compared with rank sum test. Kaplan-Meier was used to analyze the 5-year survival rate (DFS) of the two groups.
Results The levels of PT, TT and APTT in the laparoscopic group were significantly lower than those in the open group, the level of D-dimer was significantly higher than that in the open group (P<0.05), and the total complication rate in the laparoscopic group was 16.7%, which was significantly lower than that(42.9%) in the open group (P<0.05).
Conclusion Both the two kinds of operation for early gallbladder carcinoma have good effect, and laparoscopic cholecystectomy can significantly reduce complications.
Key words:
Cholecystectomy, laparoscopic,
Radical mastectomy,
Early gallbladder cancer,
Postoperative complications,
Treatment outcome,
Coagulation function
Daping Xin, Bin Peng, Ming Huang, Jiajia Zheng. Effect and long term survival analysis of different surgical methods on patients with early gallbladder carcinoma[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(03): 241-243.