Abstract:
Objective To evaluate the short and medium-term efficacy of allograft of blood vessel during radical resection for pancreatic cancer with portal vein involvement.
Methods 22 patients with pancreatic cancer with portal vein involvement received selective radical resection for pancreatic cancer in our hospital from March 2013 to May 2017 were selected and analyzed. They were given intraoperative allograft of blood vessel and postoperative follow-up. All patients were divided into type I group (15 cases) and type Y group (7 cases) according to the implanted vascular morphology. SPSS 24.0 software was used for data processing, the perioperative indexes were expressed as (±s), and the independent t test was adopted. The postoperative pathological findings, complications and postoperative short and medium-term survival rate werecompared with χ2 test, and P<0.05 was considered statistically significant.
Results There was no statistical difference in the operation time, length of vessel resection, hospital stays between the two groups groups (P>0.05); The bleeding volume and portal vein block time in type I group were lower than those in type Y group (P<0.05); The postoperative pathological results confirmed that the R0 resection rate of 22 patients with malignant pancreatic cancer was 81.8%, and the total incidence of complications was 22.7% (5/22); The postoperative mean survival time was (15.2±1.1) months; There was no statistical difference in the postoperative 3, 6, 12 m disease free survival between type I group and type Y group (P>0.05).
Conclusion Allograft of blood vessel during radical resection for pancreatic cancer involving portal vein has high R0 resection rate, less complications and high survival rate; Type I vascular implantation has lower bleeding volume and shorter portal vein block time, while type Y vascular implantation can provide the substitutes for some complicated portal system reconstruction.
Key words:
Pancreatic neoplasms,
Hypertension, portal,
Vascular grafting,
Transplantation, homologous,
Prognosis
Ling Lang. The short and medium-term follow-up of allograft of blood vessel during radical resection for pancreatic cancer with portal vein involvement[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(06): 610-613.