右半结肠癌根治术的预后一直是国内外关注的焦点与热点，目前国际上所认可的和完整系膜切除(CME)和D3淋巴结清扫术两种手术理念，能明显降低患者术后局部复发率，提高生存率及无病生存率等。但对二者术式的选择、手术入路的选择、扩大根治肠段切除和淋巴清扫范围及第6组淋巴结清扫与否等一系列问题，目前还有很多争议。同时随着腹腔镜技术的快速发展，单纯的追求微创理念已逐渐转变成更加规范和更加标准的根治理念。笔者结合长期的实践，推荐个性化手术治疗策略，以尽可能确保手术的安全性和根治的彻底性。

The prognosis of radical resection of right colon cancer has always been the focus of attention at home and abroad. At present, the concepts of Complete Mesocolic Excision (CME) and D3 lymph node dissection have been recognized generally that it could significantly reduce the postoperative local recurrence rate, improve survival rate and disease-free survival rate. However, there are still many controversies, including the options of surgical method and approach, the extent of radical colon resection and lymphadenectomy such as NO.6 lymph nodes. At the same time, with the rapid development of laparoscopy technology, the simple pursuit of minimally invasive concept has gradually turned into a more standardized radical resection concept. Based on long-term clinical practice, the authors recommended individualized surgical treatment strategies to ensure the safety and thoroughness of the operation as far as possible.