探讨病变部位对直肠癌根治性切除术的治疗效果。

回顾性分析2011年1月至2017年3月经直肠癌根治性切除术治疗的直肠癌患者186例资料，根据病变部位的差异分为低位组(低位直肠癌，即病变部位距齿状线≤5 cm，101例)和中高位组(中高位直肠癌，即病变部位距齿状线>5 cm，86例)。应用SPSS 20.0统计学软件进行统计学处理，肿瘤直径以(±s)表示，采用独立t检验；病理分期、TNM分期及病理学类型以[例(%)]表示，采用χ²检验，应用Kaplan－Meier生存曲线分析病变部位与总生存期的关系，P<0.05表示差异有统计学意义。

低位直肠癌患者的1年(82.2%)、3年(51.5%)、5年(13.9%)生存率均显著低于中高位组(100%、89.4%、21.1%)差异有统计学意义(P<0.05)，尤其是在前3年更为突出。

病变部位对直肠癌根治性切除术的治疗效果有影响，低位直肠癌患者预后较差。

To investigate the therapeutic effect of different location of rectal cancer with radical resection.

186 cases of rectal cancer treated in our hospitalfrom Jan 2011 to Mar 2017were retrospectively analyzed, according to the different location of the rectal cancer, they were divided into low group (low rectal cancer, pathological changes of the dentate line≤5 cm, 101 cases) and middle-high group (middle-high rectal cancer, pathological changes of the dentate line>5 cm, 86 cases). Statistical analysis were performed by using SPSS 20.0 software, diameter of tumor was presented as (±s) and examined by using t test; the pathological stage, TNM stage and pathological type was presented as [n(%)] and examined by chi square test, the relationship between different location and overall survival rate was analyzed by Kaplan-Meier survivor ship curve. A P<0.05 was considered as significant difference.

The 1-year (82.2%), 3-year (51.5%) and 5-year (13.9%) survival rates of low rectal cancer patients were significantly lower than those of middle and high rectal cancer patients (100%, 89.4%, 21.1%), and the difference was statistically significant (P<0.05), especially within the first three years.

The location of the lesion has an effect on the curative effect of radical resection for rectal cancer, and the prognosis of patients with low rectal cancer is poor.