To investigate the clinical significance of total mesorectal excision (TME) with preservation of Denonvilliers’ fascia guided by Wei’s line.

A retrospective analysis was performed on the clinical data of 60 male patients with mid-low rectal cancer from April 2022 to May 2023. The patients were divided into the observation group (n=30, receiving laparoscopic TME with preservation of Denonvilliers’ fascia guided by Wei’s line) and the traditional group (n=30, receiving traditional laparoscopic TME) according to different surgical protocols. Data were processed using SPSS 22.0 statistical software. Measurement data conforming to normal distribution (such as operation time and intraoperative blood loss) were expressed as (±s), and independent sample t tests were used; enumeration data (such as postoperative complications) were expressed as [cases (%)], and χ² test or Fisher’s exact probability method was applied. P<0.05 was considered statistically significant.

The operation time of the observation group was significantly longer than that of the traditional group, the intraoperative blood loss was significantly less, and the time to first anal exhaust and ambulation after surgery were significantly shorter (P<0.05). The total incidence of postoperative complications in the observation group was lower than that in the traditional group (6.7% vs. 16.7%), but the difference was not statistically significant (P>0.05). The free urinary flow rate and urine volume of both groups significantly decreased, and residual urine volume significantly increased compared with those before treatment (P<0.05), and the degree of decline in the observation group was less than that in the traditional group (P<0.05). The incidence rates of erectile dysfunction and ejaculatory dysfunction at 12 months after surgery in the observation group were significantly lower than those in the traditional group (P<0.05).

Laparoscopic TME with preservation of Denonvilliers’ fascia guided by Wei’s line for male patients with mid-low rectal cancer has a low total incidence of complications, can significantly reduce the impact on male urological and sexual functions, and promote early rehabilitation of patients.