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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (02): 205-207. doi: 10.3877/cma.j.issn.1674-3946.2020.02.028

Special Issue:

• Original Article • Previous Articles     Next Articles

A prospective control study of radiofrequency ablation and laparoscopic surgery in the treatment of primary small liver cancer

Zhiquan Chen1,(), Xuejun Liu1, Azizi Munugen1, Yongbo Wang2   

  1. 1. First general surgery department, Akesu city first people’s Hospital, Akesu area, Xinjiang Province, 843000
    2. Ankang City Hospital of traditional Chinese medicine, Ankang City, Shaanxi Province, 725022
  • Received:2019-01-09 Online:2020-04-26 Published:2020-04-26
  • Contact: Zhiquan Chen
  • About author:
    Corresponding author: Chen Zhiquan , Email:
  • Supported by:
    Project of Ankang Science and Technology Bureau(No. 2106AK|03|08)

Abstract:

Objective

To explore the clinical efficacy and safety of radiofrequency ablation and laparoscopic surgery in the treatment of primary small liver cancer.

Methods

105 cases of primary small liver cancer from June 2013 to June 2016 in our hospital were selected as the research object, the patients were randomly divided into radiofrequency ablation group (54 cases) and laparoscopic surgery group (51 cases). SPSS19.0 was used to analyzed the difference between the two groups with surgery and preoperative and postoperative liver function, survival time and complications of surgery. P<0.05 indicated the difference was statistically significant.

Results

The operation time, blood loss, infusion volume, hospitalization time in the radiofrequency ablation group was significantly lower than those in the laparoscopic surgery group (P< 0.05). the ALT and AST levels at 1 month after operation were significantly decreased in the radiofrequency ablation group than those in the laparoscopic surgery group (P<0.05). All 105 patients were followed up for 1~3 years. The tumor free survival time and overall survival time was significantly better in the radiofrequency ablation group than those in the laparoscopic surgery group (P<0.05). There was no significant difference between the two groups in complications (P>0.05).

Conclusion

Compared with laparoscopic surgery, radiofrequency ablation in small hepatocellular carcinoma treatment is safe, which can promote the recovery of liver function, improve the quality of life of patients.

Key words: Liver neoplasms, Ablation techniques, Laparoscopes, Hepatectomy, Prospective studies

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