With the continuous improvement of laparoscopic instruments and techniques, laparoscopic hepatectomy has been applied more and more in the treatments for benign and malignant liver diseases, as well as the harvest of donor liver for liver transplantation. Laparoscopic hepatectomy could be divided into anatomic and non-anatomic hepatectomy, depending on whether the liver is pre-dissected or blocked from inflow and/or outflow, with their own indications, advantages and disadvantages. Based on literature and initial experience, the advantages and disadvantages of laparoscopic anatomic and non-anatomic liver resection were reviewed in this paper.