To observe the application effect of laparoscopy combined with ultra-thin choledochoscope in patients with common bile duct stones and gallbladder stones.

118 patients with common bile duct stones and gallbladder stones were selected and divided into the observation group (treated with laparoscopy + ultra-thin choledochoscope for exploration and stone removal through the gallbladder and common bile duct) and the control group (treated with laparoscopy + choledochoscope incision for stone removal). Each group consisted of 59 patients. The differences in perioperative indicators and postoperative complications between the two groups were compared using the χ² test; the differences in inflammatory and stress response indicators between the two groups were compared using the independent sample t test.

The total effective rate of the observation group and the control group was 96.6% and 93.2% respectively, with no statistically significant difference (P>0.05), but the improvement rate of the observation group was higher than that of the control group (P<0.05). Compared with the control group, the observation group had less intraoperative blood loss, better intestinal recovery and shorter hospital stay (P<0.05), and lower levels of postoperative procalcitonin (PCT), C-reactive protein (CRP), norepinephrine (NE), cortisol (COR), epinephrine (AD) and complication rates (P<0.05).

Laparoscopy combined with ultra-thin choledochoscope exploration and stone removal through the gallbladder and common bile duct can effectively reduce the intraoperative trauma of patients with common bile duct stones and gallbladder stones, improve inflammation and stress response, and have fewer complications.