Abstract:
Objective
Compare the clinical application effects of laparoscopic anatomical hepatectomy for hepatocellular carcinoma via the approach along the main trunk of the hepatic vein and the traditional approach.
Methods
Retrospectively analyze the data of 112 patients with hepatocellular carcinoma who were diagnosed and underwent laparoscopic anatomical hepatectomy from January 2021 to December 2023.According to the different surgical approaches，they were divided into the hepatic vein group（n=56 cases，via the approach along the main trunk of the hepatic vein） and the traditional group （n=56 cases，via the traditional approach）.The statistical software SPSS 25.0 was used to process the data.Measurement data such as perioperative indexes and liver function indexes were described as （![]()
±s）.The paired sample t test was performed within the group，and the independent sample t test was performed between the groups.Count data such as the postoperative complications were described by frequency and percentage，and the χ2 test was performed.A P value less than 0.05 indicated that the difference was statistically significant.
Results
The operation time of patients in the hepatic vein group was shorter than that in the traditional group，and the intraoperative blood loss was less than that in the traditional group （P＜0.05）.Seven days after the operation，the levels of alanine aminotransferase （ALT） and aspartate aminotransferase （AST） in both groups increased compared with those before the operation，but the levels in the hepatic vein group were lower than those in the traditional group （P＜0.05）.There was no statistically significant difference in the incidence of major postoperative complications between the traditional group and the hepatic vein group （12.5% vs. 7.1%）（P＞0.05）.
Conclusion
For patients with hepatocellular carcinoma，laparoscopic anatomical hepatectomy via the approach along the main trunk of the hepatic vein has a shorter operation time and less intraoperative blood loss compared with the traditional approach.Moreover，it can reduce the damage to liver function caused by surgical procedures and has good safety.
Key words:
Carcinoma,Hepatocellular,
Laparoscopes,
Hepatectomy,
Postoperative Complications
Chao Lu, Bo Chen, Zhixiang Xing, Peng Zhou, Shuai Wang. Clinical comparison of laparoscopic anatomical hepatectomy for hepatocellular carcinoma under different approaches[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(03): 254-257.