Abstract:

Objective

To explore the influence of laparoscopic radical resection of rectal cancer with preservation of the ascending branch of the left colic artery on the surgical stress response and anal function of patients.

Methods

The data of 98 patients who underwent laparoscopic radical resection of rectal cancer from January 2021 to December 2023 were collected.Among them，50 patients with preservation of the left colic artery were in the observation group，and 48 patients without preservation of the left colic artery were in the control group.The surgical indexes of the two groups of patients，the surgical stress response at 1 day and 7 days after surgery，the anal function before surgery and 1 month after surgery，and the occurrence of postoperative complications were compared.The statistical software SPSS 25.0 was used to process the data.Independent samples t test was used for surgical indexes，surgical stress，and anal function，etc.Postoperative complications were expressed as ［cases （%）］，and the chi-square test was used.A P value less than 0.05 was considered statistically significant.

Results

The operation time of the observation group was significantly longer than that of the control group （P＜0.05）.At 1 day after surgery，the levels of norepinephrine （NE），cortisol （Cor），and epinephrine （E） in the observation group were higher than those in the control group （P＜0.05）.At 7 days after surgery，the levels of Cor，E，and NE in both groups decreased compared with those at 1 day after surgery （P＜0.05）；and there was no statistically significant difference in the levels of Cor，E，and NE between the two groups （P＞0.05）.One month after surgery，the scores of rectal anterior resection syndrome in both groups increased compared with those before surgery，but the scores in the observation group were lower than those in the control group.The resting pressure （RP） and maximum systolic pressure （MSP） of the anal canal in both groups decreased compared with those before surgery，but the values in the observation group were higher than those in the control group （P＜0.05）.There was no statistically significant difference in the incidence of complications between the two groups （P＞0.05）.

Conclusion

Laparoscopic radical resection of rectal cancer with preservation of the ascending branch of the left colic artery can promote the recovery of anal function with definite curative effect.However，it has a long operation time and can increase the surgical stress response to a certain extent.

Key words: Rectal Tumor, Rectal Cancer Radical Surgery, Laparoscopes, Left Colonic Artery, Surgical Stress, Anal Function