Abstract:
Objective
To compare the efficacy of two different spleen-preserving distal pancreatectomies in the treatment of tumors of the body and tail of the pancreas.
Methods
The data of 87 patients who underwent spleen-preserving distal pancreatectomy from January 2020 to December 2022 were retrospectively analyzed.According to different surgical methods，they were divided into the Kimura group （n=44 cases） and the Warshaw group （n=43 cases）.The SPSS25.0 software was used for data analysis.Measurement data such as perioperative indicators and immune function indicators were expressed as （![]()
±s），and the independent-sample t test was performed.Count data such as the occurrence of postoperative complications，recurrence rate during follow-up，and re-operation status were analyzed by the χ2 test.A P value＜0.05 was considered statistically significant.
Results
The operation time of patients in the Kimura group was longer than that in the Warshaw group （P＜0.05）.There was no significant difference in intraoperative blood loss and the time of anal flatus between the two groups （P＞0.05）.The time of first getting out of bed，the time of drainage tube removal，and the postoperative hospital stay of patients in the Kimura group were all shorter than those in the Warshaw group （P＜0.05）.On the first day after surgery，the levels of CD3+，CD4+，and CD4+/CD8+ in both groups decreased compared with those before surgery，but the levels in the Kimura group were higher than those in the Warshaw group （P＜0.05）.The incidence of postoperative complications in the Kimura group was 4.6% （2/44），which was lower than 20.9% （9/43） in the Warshaw group （P＜0.05）.During the follow-up period，neither group had recurrence or re-operation.
Conclusion
Both spleen-preserving distal pancreatectomies can achieve ideal efficacy in the treatment of tumors of the body and tail of the pancreas.Compared with the Warshaw procedure，although the Kimura procedure has a longer operation time，it can avoid a significant decline in postoperative immune function，reduce the occurrence of postoperative complications，and promote the early recovery of patients.
Key words:
Pancreatic Neoplasms,
Spleen-Preserving Distal Pancreatectomy,
Blood Loss,Surgical,
Postoperative Complications,
Recurrence
Jianxiong Li, Jiang Zhou, Tao Li, Peiyu Qiao, Xin Tang, Ming Dong. Clinical comparison of two different spleen-preserving distal pancreatectomies for tumors of the body and tail of the pancreas[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(03): 325-328.