To explore the efficacy and advantages of clinical application of laparoscopic anatomic left hepatectomy through Glisson pedicle extrathecal anatomy and Laennec membrane approach.

The data of 40 patients who underwent laparoscopic left hepatectomy from June 2018 to June 2023 were retrospectively analyzed, and the patients were divided into group A (laparoscopic anatomic left hepatectomy through Glisson pedicle extrathecal anatomy and Laennec membrane approach) and group B (Pringle total hepatic blood flow blockade, left hepatectomy through Glisson pedicle extrathecal anatomy), with 20 cases in each group. SPSS 24.0 software was used for data analysis. Measurement data such as perioperative indicators and preoperative and postoperative liver function indicators were expressed as (), and independent t test was adopted for between-group comparison. Postoperative complications and other enumeration data were represented as [n (%)], and χ² test was used for comparison between the two groups. P<0.05 was considered statistically significant.

The surgical time in group A was shorter compared with that in group B, and the intraoperative blood loss volume, blood transfusion volume and blood transfusion rate were less than those in group B (P<0.05). The liver function indicators after surgery in group A were lower than those in group B (P<0.05). There were no statistically significant differences in postoperative hospital stay, drainage tube retention time and gastrointestinal recovery time between the two groups (P>0.05). The total incidence rate of postoperative complications was lower in group A (10%) than that in group B (40%) (P<0.05).

Laparoscopic anatomic left hepatectomy through Glisson pedicle extrathecal anatomy and Laennec membrane approach has feasibility, safety and effectiveness in clinical application, with rapid postoperative recovery and few complications.