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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2023, Vol. 17 ›› Issue (05): 497-501. doi: 10.3877/cma.j.issn.1674-3946.2023.05.008

• Original Article • Previous Articles     Next Articles

Meta-analysis of the effect of Denonvilliers’ fascia preservation versus resection during laparoscopic total mesorectal excision on male urination and sexual function

Haibo Xiong, Lihao Deng, Libin Deng, Yunlong Zeng, Shuqiang Li, Zhenghong Qiang, Jiatian Yuan, Bo Lv, Jun Li()   

  1. Department of Gastroenterology, Affiliated Hospital of Chengdu University, Chengdu Sichuan 610061, China
  • Received:2022-11-14 Online:2023-10-26 Published:2023-09-11
  • Contact: Jun Li
  • Supported by:
    2022 hospital-level Research Project of Clinical College of Medicine and Affiliated Hospital of Chengdu University(Y202236)

Abstract:

Objective

A meta-analysis was performed to evaluate the effects of preserving and removing denonvilliers fascia(DVF)during laparoscopic radical surgery on urination and sexual function in male patients with rectal cancer.

Methods

By searching large literature databases such as Pubmed,FMRS Library,Wanfang,Weipu,CNKI,etc.,the literature search started and ended from the establishment of the database to August 2022. Meta-analysis was performed using Revman 5.3 software,and Begg's test was performed using STATA14.0 to evaluate publication bias among studies.

Results

A total of 915 patients in 9 literatures were included. The experimental group retained DVF(n=457 cases)and the control group did not retain DVF(n=458 cases). The incidence of urinary dysfunction,sexual dysfunction and ejaculatory dysfunction in the experimental group was significantly lower than that in the control group,and the difference was statistically significant(Z=5.92,2.82,5.69; P<0.05),the experimental group had higher maximum urinary flow and international erectile function questionnaire scores,and the differences were statistically significant(Z=12.32,5.34; P<0.05). Sensitivity analysis was carried out after the relevant literatures were excluded one by one,and there was no significant change in the comparison of the final statistical results. The funnel plot of Begg's test indicating ejaculatory dysfunction showed no publication bias(P=0.315).

Conclusion

Retention of DVF during laparoscopic radical resection of rectal cancer can effectively protect the function of pelvic autonomic nerve in male patients,so as to more effectively avoid the occurrence of postoperative urination function and sexual dysfunction.

Key words: Rectal Neoplasms, Denonvilliers’ Fascia, Laparoscopes, Urinary Function, Sexual Dysfunction

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