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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2023, Vol. 17 ›› Issue (02): 226-229. doi: 10.3877/cma.j.issn.1674-3946.2023.02.028

• Review • Previous Articles     Next Articles

Current situation and prospect of indocyanine green for surgical nerve imaging

Song Liu1, Qiongyuan Hu1, Xiaofeng Lu1, Wenxian Guan1,()   

  1. 1. Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing Jiangsu Province 210008, China
  • Received:2022-12-19 Online:2023-04-26 Published:2023-03-30
  • Contact: Wenxian Guan
  • Supported by:
    National Natural Science Foundation of China(82172645); Key Research and Development Program of Jiangsu Province(Social Development)(BE2022667); Key Research and Development Program of Jiangsu Province(Frontiers in Clinical Technology)(BE2022753); Natural Science Foundation of Jiangsu Province for Outstanding Young Scholars(BK20200052)

Abstract:

Neuroprotection plays an important role in surgery and is closely related to perioperative safety and physiological function. Indocyanine green(ICG)as the representative of near infrared fluorescence tracer has been widely used in clinic. Previous studies mainly focus on the tumor imaging and lymphatic tracer function of ICG. This paper reviews the application history of ICG in the field of navigation surgery,reviews the clinical evidence of ICG in intraoperative nerve development and protection,and focuses on summarizing the principle,administration mode and observation window of ICG nerve development. The prospects of clinical application of new tracers derived from ICG and ICG near infrared Ⅱ imaging are prospected.

Key words: Indocyanine Green, NIR-Ⅱ, Fluorescence-Guided Surgery, Nerve Visualization

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