Surgical resection is the only potential method to cure pancreatic cancer. In the past 10 years，minimally invasive pancreatic resection（including laparoscopy and robotics）has developed rapidly and made great progress. It has become one of the treatment options of pancreatic cancer in larger pancreatic centers. Although minimally invasive pancreatectomy has shown some advantages in perioperative variables compared with the open approach，there are still controversies on the oncological outcomes. The existing evidence of evidence-based medicine is mainly single center，retrospective research，and most of them enrolled mixed pathological types. Therefore，whether minimally invasive radical resection of pancreatic cancer can bring benefits in oncology efficacy must be answered through high-quality randomized controlled studies. The design and implementation of high-quality clinical research and the strengthening of multi-center cooperation will help to enhance the individualized application of minimally invasive technology in pancreatic cancer resection and enhance China’s international influence in this field.