To investigate the clinical effects of Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG) in the treatment of recurrent obesity hyperlipidemia acute pancreatitis (HLAP).

A retrospective study was conducted in 89 patients with recurrent obesity HLAP who underwent surgical treatment from October 2015 to October 2019. According to different surgical procedures, the patients were divided into LRYGB group (49 cases) and LSG group (40 cases), while patients underwent Laparoscopic Roux-en-Y gastric bypass surgery in the LRYGB group and patients underwent laparoscopic sleeve gastrectomy in the LSG group. Data analysis were performed by using SPSS 25.0 software. Measurement data, such as surgery-related indicators, weight loss effects, lipid-lowering effects, and glucose-lowering effects, were expressed as. The independent sample t-test was used for comparison between two groups. A P value of <0.05 was considered as statistically significant difference.

Compared with the LRYGB group, there were lower level in terms of intraoperative blood loss, operation time, time to get out of bed, anal exhaust time, and hospital stay in the LSG group respectively (P<0.05). There was no significant difference between two groups at 3 months after operation in terms of the percentage of extra body weight loss (EWL), body weight, body mass index (BMI), total cholesterol (TC), and triglycerides (TG) (P>0.05). Compared with the LSG group, there were lower level of the fasting blood glucose (FPG), fasting insulin (FINS), and oral glucose tolerance test (OGTT) at 3 months after operation in the LRYGB group respectively, with significant differences (P<0.05).

Both LRYGB and LSG could achieve similar clinical effects in weight loss and lipid lowering in the treatment of repeated obesity-type acute hyperlipidemia pancreatitis, however LSG has simpler operation and quicker postoperative recovery, and LRYGB has Certain advantages in hypoglycemic aspects.