To explore the clinical effects of Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG) in the treatment of recurrent obesity hyperlipidemic acute pancreatitis (HLAP).

The clinical data of 89 patients with recurrent obesity HLAP who underwent surgical treatment from October 2015 to October 2019 was divided into LRYGB group (49 cases) and LSG group (40 cases) according to different surgical procedures. Laparoscopic Roux-en-Y gastric bypass surgery was used in the LRYGB group, and laparoscopic sleeve gastrectomy was used in the LSG group. SPSS 25.0 software was used for data processing. Surgery-related indicators, weight loss effects, lipid-lowering effects, and glucose-lowering effects were expressed as (±s). Independent sample t test was used for comparison between groups, and P<0.05 was considered statistically significant.

The intraoperative blood loss, operation time, time of getting out of bed, anal exhaust time, and hospital stay in the LSG group were all lower than those in the LRYGB group, with statistical significance (P<0.05). There was no significant difference in the percentage of extra body weight loss (EWL), body weight, body mass index (BMI), total cholesterol (TC), and triglycerides (TG) between the two groups at 3 months after operation (P>0.05). Three months after operation, the fasting blood glucose (FPG), fasting insulin (FINS), and oral glucose tolerance test (OGTT) in the LRYGB group were lower than those in the LSG group, with statistical significance (P<0.05).

LRYGB and LSG have similar clinical effects in weight loss and lipid reduction in the treatment of HLAP with repeated obesity, but LSG has simpler operation and quicker postoperative recovery, while LRYGB has Certain advantages in hypoglycemic aspects.