To investigate the effect of laparoscopic complete exocyst dissection in the treatment of hepatic echinococcosis and its influence on liver function and prognosis.

The clinical data of 109 patients with hepatic echinococcosis admitted to our hospital from October 2018 to October 2021 were retrospectively analyzed. Patients were divided into laparotomy group (n=54, laparotomy) and endoscopy group (n=55, complete exfoliation of external capsule by laparoscopy) according to different surgical methods. SPSS 22.0 software was used to analyze the data. Perioperative indicators, liver function indicators, stress response indicators and other measurement data were described as (), and independent sample t test was used. The statistical data of complications were shown as [n (%)] and χ² test was performed. P<0.05 was considered to be statistically significant.

The intraoperative blood loss in the endoscopic group was less than that in the laparotomy group, and the postoperative hospitalization time, getting out of bed time and anal exhaust time were significantly lower than those in the laparotomy group (P<0.05). The operation time of endoscopic group was longer than that of laparotomy group (P<0.05). On the 7th day after operation, the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), interleukin-6(IL-6), tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) in 2 groups were higher than those before operation, and albumin (ALB) was lower than those before operation (P<0.05). However, the levels of ALT, AST, TBIL, IL-6, TNF-α and CRP in endoscopic group were significantly lower than those in open group, and ALB was higher than those in open group (P<0.05). The total incidence of complications in the endoscopic group was 5.5%, with no recurrence within 1year; the total incidence of complications in the laparotomy group was 18.5%, and the recurrence rate was 3.7%; the total incidence of complications in the endoscopic group was lower than that in the laparotomy group (P<0.05), and there was no statistical significance in the recurrence rate between the two groups (P>0.05).

Laparoscopic complete removal of external capsule in the treatment of hepatic echinococcosis has significant clinical effect, which can reduce the stress response of patients, and has relatively little influence on postoperative liver function indicators, which has positive significance in improving the short-term prognosis of patients.