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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (02): 150-153. doi: 10.3877/cma.j.issn.1674-3946.2021.02.010

Special Issue:

• Original Article • Previous Articles     Next Articles

Clinical evaluation of Modified Devine exclusion for patients with unresectable distal gastric cancer

Wei Wang1, Chengmin Ma2, Dong Tang1, Liuhua Wang1, Qingyang Meng1, Daorong Wang1,()   

  1. 1. YangZhou University-Yangzhou Institute of General Surgery, Subei People's Hospital of Jiangsu province, Yangzhou University Clinical Medical College, Jiangsu 225001, China
    2. Yangzhou Clinical Medical College of Dalian Medical University, Liaoning 116044 , China
  • Received:2020-06-19 Online:2021-04-26 Published:2021-04-25
  • Contact: Daorong Wang
  • Supported by:
    National Natural Science Foundation of China(81871317)

Abstract:

Objective

To investigate the safety and feasibility of two different surgical methods for patients with unresectable distal gastric cancer.

Methods

Clinical data of 61 patients with unresectable distal gastric cancer who underwent surgical treatment from September 2012 to September 2019 were analyzed retrospectively. Among them, 25 cases underwent modified Devine operation (modified group), and 36 cases underwent traditional gastrojejunostomy (traditional group). Statistical analysis were performed by using SPSS21.0 software package. The perioperative indicators were expressed as (±s) and were analyzed by using independent sample t-test. The postoperative complications were compared by using χ2 test. The postoperative satisfaction of patients were compared by using Mann-Whitney U test. A P value of <0.05 was considered as statistically significant difference.

Results

There were no significant difference between two groups, in terms of the average operation time, blood loss, postoperative ventilation time, eating time, hospitalization time and ALB increase at 1 month after operation (P>0.05). There were 6 cases (16.7%) of gastric emptying disorder in the traditional group, while no gastric emptying disorder occurred in the modified group, with statistically significant difference (P=0.032). The total postoperative complication rate of 4.0% in the improved group was significantly lower than 22.2% in the traditional group, with statistically significant difference (P=0.048). The postoperative satisfaction of patients in improved group was signifcantly high than that in traditional group, with statistically significant difference (P=0.016).

Conclusion

Modified Devine operation could significantly relieve the symptoms and reduce the postoperative complications and improve satisfaction. It is a safe and effective surgical method, which is worthy of promotion and application.

Key words: Stomach neoplasms, Gastroenterostomy, Comparative effectiveness research, Modified devine exclusion

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