Abstract:
Objective To study the short-term effect of three kinds of biliary drainage on obstructive jaundice and influence of postoperative liver function.
Methods The clinical data of 106 patients with malignant obstructive jaundice from July 2016 to June 2019 were analyzed retrospectively. The patients were divided into three groups according to their treatment methods: ERCP group, PTCD group and EUS-BD group. The data were analyzed by SPSS24.0 statistical software. Among them, hospitalization time and liver function index were expressed by (±s). The data among three different groups were compared by one-way ANOVA, two different data in one group were compared by LSD-t test. The incidence of postoperative complications was compared by χ2 test. P<0.05 was considered statistically significant.
Results All the patients in the three groups completed the operation successfully, and all the clinical symptoms were relieved. The average hospitalization days of the three groups showed as: EUS-BD group<ERCP group<PTCD group (P<0.001). All indexes of liver function in the three groups decreased significantly on day 7 after surgery, and the differences were statistically significant compared with those before surgery (P<0.05). The total remission rate was 74.3% (26/35) in the ERCP group, 77.3% (34/44) in the PTCD group and 77.8% (21/27) in the EUS-BD group (P>0.05). The incidence of postoperative complications was 14.3% in the ERCP group, 34.1% in the PTCD group, and 7.4% in the EUS-BD group, with statistically significant differences (P=0.013).
Conclusion ERCP, PTCD and EUS-BD drainage have the same short-term therapeutic effect on malignant obstructive jaundice, while EUS-BD has less complications, faster recovery and greater advantages.
Key words:
Cholangiopancreatography, endoscopic retrograde,
PTCD,
EUS-BD,
Liver function,
Comparative effectiveness research
Yu Cai, Pu Yan, Wu Jun Li, Xiaowei Chang, Huan Jia, Lin Yang. The short-term effect of three kinds of biliary drainage on obstructive jaundice and influence of postoperative liver function[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(05): 504-507.